U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 7031 - 7040 of 9777 results

Status:
Investigational
Source:
INN:alipamide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Alipamide is an antihypertensive and diuretic agent. It is a hydrazide derivative of m-sulfamoylbenzoic acid with diuretic activity. Alipamide primarily causes a saluretic effect and is able to inhibit carbonic anhydrase at higher doses which may also contribute to this agent's diuretic effect.
Status:
Investigational
Source:
INN:nimazone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Nimazone is an anti-inflammatory drug.
Status:
Investigational
Source:
INN:amquinate
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Amquinate is a quinolone coccidiostat. It is a powerful inhibitior of succinate and malate plus pyruvate supported respiration in E. tenella mitochondria. Amquinate is an antimalarial drug.
Status:
Investigational
Source:
NCT02102178: Phase 2 Interventional Completed Cancer
(2007)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT01393678: Phase 3 Interventional Completed Chronic Liver Disease
(1997)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

BIPHENYL DIMETHYL DICARBOXYLATE (BDD) under the brand name Nissel is used in the South Corea for the treatment of chronic hepatitis followed by an increase in serum alanine aminotransferase levels continuously. This compound also participated in clinical trials phase III in the patients with chronic liver disease. In addition, the drug was studied in phase III clinical trials after laparoscopic cholecystectomy. The use of BDD in patients with cholecystitis was expected to inhibit elevated liver enzyme levels and to maintain liver function.
Status:
Investigational
Source:
INN:cortodoxone
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



11-Deoxycortisol (also known as cortodoxone) is the predominant deoxycorticosteroid and is the immediate precursor of cortisol, which is formed by the enzymatic action of 11beta-hydrozylase (P450). Deficiency of this enzyme causes congenital adrenal hyperplasia, which is characterized by hypertension. 11-deoxycortisol is measured as part of the Metyrapone Test. Metyrapone blocks the formation of cortisol, resulting in increased secretion of Adrenocorticotropic hormone (ACTH) and 11-deoxycortisol in normal individuals.
Status:
Investigational
Source:
NCT00002175: Phase 1 Interventional Completed HIV Infections
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Dinitrochlorobenzene (DNCB) is a chemical used in color photography processing. Dinitrochlorobenzene has been successfully used to treat warts. It requires follow-up applications that might be done either in the office by the doctor or a nurse, or at home by the patient. The therapy was working immunologically to enable the body to recognize the foreign virus. The cure is associated with normalization of the cell-mediated immune response. Some researchers and community activists proposed that when DNCB is applied to the skin once a week, it stimulates the immune system to control HIV replication and delay opportunistic infections. Some research shows that DNCB leads to increases in CD8 (T-killer or T-8) cells. Dinitrochlorobenzene is not approved by the FDA, and is considered experimental. There are possible drawbacks to this treatment. The autoeczematization is not rare. Dinitrochlorobenzene is used to induce experimental dermatitis in rats. It is a potent contact allergen.
Status:
Investigational
Source:
INN:dinsed [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Dinsed is a coccidiostat used in poultry to stop the growth of coccidian parasites.
Status:
Investigational
Source:
INN:chloropyrilene [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
Int J Oral Maxillofac Surg. Feb 2016;45(2):186-93.: Not Applicable Human clinical trial Completed Sensation Disorders/etiology
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Showing 7031 - 7040 of 9777 results