AMQUINATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H24N2O3
Molecular Weight	316.3948
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCC1=CC2=C(O)C(=CN=C2C=C1N(CC)CC)C(=O)OC

InChI

InChIKey=NMYCTBARPUAEQN-UHFFFAOYSA-N

InChI=1S/C18H24N2O3/c1-5-8-12-9-13-15(10-16(12)20(6-2)7-3)19-11-14(17(13)21)18(22)23-4/h9-11H,5-8H2,1-4H3,(H,19,21)

HIDE SMILES / InChI

Molecular Formula	C18H24N2O3
Molecular Weight	316.3948
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1171697 | https://www.genome.jp/dbget-bin/www_bget?drug+D02930 | https://www.who.int/medicines/services/inn/StemBook2009.pdf

Amquinate is a quinolone coccidiostat. It is a powerful inhibitior of succinate and malate plus pyruvate supported respiration in E. tenella mitochondria. Amquinate is an antimalarial drug.

Approval Year

PubMed

Title	Date	PubMed
Comparison of anticoccidial efficacy, resistance and tolerance of narasin, monensin and lasalocid in chicken battery trials.	1977-09	605098
Studies of the mitochondria from Eimeria tenella and inhibition of the electron transport by quinolone coccidiostats.	1975-08-11	1171697

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:35:21 GMT 2025` Edited by `admin` on `Mon Mar 31 17:35:21 GMT 2025`
Record UNII	21N28Z70CI
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-339053

Preferred Name

English

AMQUINATE

Official Name

English

amquinate [INN]

Common Name

English

AMQUINATE [USAN]

Common Name

English

3-QUINOLINECARBOXYLIC ACID 7-(DIETHYLAMINO)-4-HYDROXY-6-PROPYL-, METHYL ESTER

Common Name

English

Methyl 7-(diethylamino)-4-hydroxy-6-propyl-3-quinolinecarboxylate

Systematic Name

English

Code System Code Type Description

ChEMBL

CHEMBL2104009