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Search results for azelaic root_codes_code in Code Literal (approximate match)
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
RU 28318 also known as OXPRENOATE is a mineralocorticoid receptor (MR) antagonist, inhibiting aldosterone production and secretion. RU 28318 has been studied in normal and diabetic rats. It was revealed, that in combination with angiotensin converting enzyme inhibitors, RU 28318 was the most effective at improving -dP/dt (a measure of diastolic function) and attenuated cardiac dysfunction in diabetes.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Benzohydroxamic acid is a bidentate chelating agent. Benzohydroxamic acid is known to be competitive inhibitors of a variety of plant and animal peroxidases. Benzohydroxamic acid did not show a bactericidal effect against Helicobacter pylori despite moderate inhibition of urease activity. Benzohydroxamic acid is used for the synthesis of histone deacetylase inhibitors. Benzohydroxamic acid derivatives demonstrated the antineoplastic and cytotoxicity in murine and human tumor cells.
