Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H3FO2 |
| Molecular Weight | 78.0424 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CF
InChI
InChIKey=QEWYKACRFQMRMB-UHFFFAOYSA-N
InChI=1S/C2H3FO2/c3-1-2(4)5/h1H2,(H,4,5)
| Molecular Formula | C2H3FO2 |
| Molecular Weight | 78.0424 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| ATP signalling in epilepsy. | 2008-12 |
|
| Metabolic challenge to glia activates an adenosine-mediated safety mechanism that promotes neuronal survival by delaying the onset of spreading depression waves. | 2008-11 |
|
| Bell-shaped D-serine actions on hippocampal long-term depression and spatial memory retrieval. | 2008-10 |
|
| Phase I/II study of oxaliplatin with oral S-1 as first-line therapy for patients with metastatic colorectal cancer. | 2008-03-25 |
|
| Nanomosaic: formation of nanodomains confined in a two-dimensional molecular plane. | 2008-03-04 |
|
| [Breeding of monofluoroacetate-resistant strains of Actinobacillus succinogenes and the mechanism based on metabolic flux analysis]. | 2008-03 |
|
| Degradation of 4-fluorophenol by Arthrobacter sp. strain IF1. | 2008-03 |
|
| Glycine uptake regulates hippocampal network activity via glycine receptor-mediated tonic inhibition. | 2008-02 |
|
| Incorporation of fluoroacetate into an aromatic polyketide and its influence on the mode of cyclization. | 2008 |
|
| Stress preconditioning of spreading depression in the locust CNS. | 2007-12-26 |
|
| Astrocytes play a critical role in transient heterosynaptic depression in the rat hippocampal CA1 region. | 2007-12-15 |
|
| Mechanism of enzymatic fluorination in Streptomyces cattleya. | 2007-11-28 |
|
| The fate of the chemical warfare agent during DNA extraction. | 2007-11 |
|
| (18)F-labeled positron emission tomographic radiopharmaceuticals in oncology: an overview of radiochemistry and mechanisms of tumor localization. | 2007-11 |
|
| Hyperammonemia inhibits the natriuretic peptide receptor 2 (NPR-2)-mediated cyclic GMP synthesis in the astrocytic compartment of rat cerebral cortex slices. | 2007-11 |
|
| Contactless conductivity detection of sodium monofluoroacetate in fruit juices on a CE microchip. | 2007-10 |
|
| The identification of (3R,4S)-5-fluoro-5-deoxy-D-ribulose-1-phosphate as an intermediate in fluorometabolite biosynthesis in Streptomyces cattleya. | 2007-10 |
|
| Quantitative analysis of monofluoroacetate in biological samples by high-performance liquid chromatography using fluorescence labeling with 9-chloromethylanthracene. | 2007-09-15 |
|
| Effect of metabolic inhibitors on ATP and citrate content in PC3 prostate cancer cells. | 2007-08-01 |
|
| Determination of sodium monofluoroacetate (1080) in biological samples as its 4-bromomethyl-7-methoxycoumarin derivative by RP-HPLC. | 2007-08 |
|
| Involvement of glia in central sensitization in trigeminal subnucleus caudalis (medullary dorsal horn). | 2007-07 |
|
| Unusual but potential agents of terrorists. | 2007-05 |
|
| Metabolism of mono- and dihalogenated C1 and C2 compounds by Xanthobacter autotrophicus growing on 1,2-dichloroethane. | 2007-04 |
|
| Calcium oxalate crystals and methyl salicylate as toxic principles of the fresh leaves from Palicourea longiflora, an endemic species in the Amazonas state. | 2007-03-01 |
|
| Long-term potentiation of neuronal excitation by neuron-glia interactions in the rat spinal dorsal horn. | 2007-03 |
|
| 18F-fluoroacetate: a potential acetate analog for prostate tumor imaging--in vivo evaluation of 18F-fluoroacetate versus 11C-acetate. | 2007-03 |
|
| Modulation of NMDA receptor current in layer V pyramidal neurons of the rat prefrontal cortex by P2Y receptor activation. | 2007-03 |
|
| Poly-beta-hydroxybutyrate accumulation in Nostoc muscorum: effects of metabolic inhibitors. | 2007-03 |
|
| Ecotoxicological evaluation of sodium fluoroacetate on aquatic organisms and investigation of the effects on two fish cell lines. | 2007-02 |
|
| The use of myocardial and testicular end points as a basis for estimating a proposed tolerable daily intake for sodium monofluoroacetate (1080). | 2007-02 |
|
| A benchmark dose analysis for sodium monofluoroacetate (1080) using dichotomous toxicity data. | 2007-02 |
|
| Rapid quantitative and qualitative confirmatory method for the determination of monofluoroacetic acid in foods by liquid chromatography-mass spectrometry. | 2007-01-19 |
|
| Schistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitor. | 2007-01 |
|
| [Studies of interaction of intracellular signalling and metabolic pathways under inhibition of mitochondrial aconitase with fluoroacetate]. | 2007 |
|
| In vitro induction of micronuclei by monofunctional methanesulphonic acid esters: possible role of alkylation mechanisms. | 2006-12-01 |
|
| Acceptance by stoats (Mustela erminea) of 1080 (sodium monofluoroacetate) in small-volume baits and its effect on behaviour and time to death. | 2006-12 |
|
| Scandium-catalyzed carbon-carbon bond formations using alpha-organosulfanyl and organoselanyl-alpha-fluoroacetic acid derivatives. | 2006-11 |
|
| Determination of fluoroacetic acid in water and biological samples by GC-FID and GC-MS in combination with solid-phase microextraction. | 2006-11 |
|
| The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots. | 2006-05-15 |
|
| Is fluoroacetate-specific defluorinase a glutathione S-transferase? | 2006-05 |
|
| Efficient synthesis of beta2-amino acid by homologation of alpha-amino acids involving the Reformatsky reaction and Mannich-type imminium electrophile. | 2006-04-14 |
|
| Calcium gluconate and sodium succinate for therapy of sodium fluoroacetate experimental intoxication in cats: clinical and electrocardiographic evaluation. | 2006-04 |
|
| Fluorine nuclear magnetic resonance spectroscopy of human biofluids in the field of metabolic studies of anticancer and antifungal fluoropyrimidine drugs. | 2006-04 |
|
| Uptake and persistence of the vertebrate pesticide, sodium monofluoroacetate (compound 1080), in plants of cultural importance. | 2006-02 |
|
| Characterization of the fluoroacetate detoxication enzymes of rat liver cytosol. | 2006-01-06 |
|
| New approach to fully automated synthesis of sodium [18F]fluoroacetate -- a simple and fast method using a commercial synthesizer. | 2006-01 |
|
| Sodium fluoroacetate poisoning. | 2006 |
|
| Interest of fluorine-19 nuclear magnetic resonance spectroscopy in the detection, identification and quantification of metabolites of anticancer and antifungal fluoropyrimidine drugs in human biofluids. | 2006 |
|
| Toxicology of fluoroacetate: a review, with possible directions for therapy research. | 2005-10-28 |
|
| Brain metabolism of exogenous pyruvate. | 2005-10 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:34:00 GMT 2025
by
admin
on
Mon Mar 31 18:34:00 GMT 2025
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| Record UNII |
AP1JV9U41M
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| Record Status |
Validated (UNII)
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| Record Version |
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Download
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Preferred Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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EPA PESTICIDE CODE |
75001
Created by
admin on Mon Mar 31 18:34:00 GMT 2025 , Edited by admin on Mon Mar 31 18:34:00 GMT 2025
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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m5469
Created by
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PRIMARY | Merck Index | ||
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fluoroacetic acid
Created by
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FLUOROACETIC ACID
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2082
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100000155589
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C014815
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SUB129640
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5237
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DTXSID0041981
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205-631-7
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30775
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AP1JV9U41M
Created by
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144-49-0
Created by
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |