Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C6H13O10P |
| Molecular Weight | 276.1352 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O
InChI
InChIKey=BIRSGZKFKXLSJQ-SQOUGZDYSA-N
InChI=1S/C6H13O10P/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15)/t2-,3-,4+,5-/m1/s1
| Molecular Formula | C6H13O10P |
| Molecular Weight | 276.1352 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Role of methionine-13 in the catalytic mechanism of 6-phosphogluconate dehydrogenase from sheep liver. | 2005-02-22 |
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| A novel NADPH:(bound) NADP+ reductase and NADH:(bound) NADP+ transhydrogenase function in bovine liver catalase. | 2005-02-01 |
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| Changes in the metabolome of Saccharomyces cerevisiae associated with evolution in aerobic glucose-limited chemostats. | 2005-02 |
|
| Fatty acid synthesis and the oxidative pentose phosphate pathway in developing embryos of oilseed rape (Brassica napus L.). | 2005-02 |
|
| A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum. | 2005-01-15 |
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| Estimating the number of viable animal cells in multiwell culture--a tetrazolium-based assay. | 2005-01-15 |
|
| Taxonomic note "Lactobacillus pastorianus" (Van Laer, 1892) a former synonym for Lactobacillus paracollinoides. | 2005-01 |
|
| Purification of 6-phosphogluconate dehydrogenase from chicken liver and investigation of some kinetic properties. | 2005 |
|
| Identification of proteins induced by polycyclic aromatic hydrocarbon in Mycobacterium vanbaalenii PYR-1 using two-dimensional polyacrylamide gel electrophoresis and de novo sequencing methods. | 2004-12 |
|
| Tissue distribution and evolution of fructosamine 3-kinase and fructosamine 3-kinase-related protein. | 2004-11-05 |
|
| Role of energy metabolism in the pregnancy interceptive action of Ferula assafoetida and Melia azedarach extracts in rat. | 2004-11 |
|
| 6-phosphogluconate dehydrogenase: a target for drugs in African trypanosomes. | 2004-10 |
|
| Multinuclear NMR study of the complexes of 6-phospho-D-gluconic acid with W(VI) and Mo(VI). | 2004-09-13 |
|
| Functional constraints of 6-phosphogluconate dehydrogenase (6-PGD) based on sequence and structural information. | 2004-09 |
|
| Average allozyme heterozygosity in vertebrates correlates with Ka/Ks measured in the human-mouse lineage. | 2004-09 |
|
| Effects of some antibiotics on human erythrocyte 6-phosphogluconate dehydrogenase: an in vitro and in vivo study. | 2004-08 |
|
| Upregulation of lipogenic enzymes genes expression in white adipose tissue of rats with chronic renal failure is associated with higher level of sterol regulatory element binding protein-1. | 2004-08 |
|
| The effects of n-3 polyunsaturated fatty acids by gavage on some metabolic enzymes of rat liver. | 2004-08 |
|
| Cyanobacterial genes transmitted to the nucleus before divergence of red algae in the Chromista. | 2004-07 |
|
| Metabolic regulation analysis of icd-gene knockout Escherichia coli based on 2D electrophoresis with MALDI-TOF mass spectrometry and enzyme activity measurements. | 2004-07 |
|
| Selective inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenase by high-energy intermediate and transition-state analogues. | 2004-06-17 |
|
| Factors influencing nitroxide reduction and cytotoxicity in vitro. | 2004-06 |
|
| 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy. | 2004-05-15 |
|
| Inhibitory effect of pyrimidine and purine nucleotides on the multiplication of Babesia gibsoni: possible cause of low parasitemia and simultaneous reticulocytosis in canine babesiosis. | 2004-04 |
|
| Altered activity of the P2 isoform of plastidic glucose 6-phosphate dehydrogenase in tobacco (Nicotiana tabacum cv. Samsun) causes changes in carbohydrate metabolism and response to oxidative stress in leaves. | 2004-04 |
|
| The effect of pfl gene knockout on the metabolism for optically pure D-lactate production by Escherichia coli. | 2004-04 |
|
| Genetic analysis of violacein biosynthesis by Chromobacterium violaceum. | 2004-03-31 |
|
| Effects of long-term exposure to Cu2+ and Cd2+ on the pentose phosphate pathway dehydrogenase activities in the ovary of adult Bufo arenarum: possible role as biomarker for Cu2+ toxicity. | 2004-03 |
|
| Global metabolic response of Escherichia coli to gnd or zwf gene-knockout, based on 13C-labeling experiments and the measurement of enzyme activities. | 2004-03 |
|
| The 6-phosphogluconate dehydrogenase from Trypanosoma cruzi: the absence of two inter-subunit salt bridges as a reason for enzyme instability. | 2004-02 |
|
| Glucose-6-phosphate isomerase from the hyperthermophilic archaeon Methanococcus jannaschii: characterization of the first archaeal member of the phosphoglucose isomerase superfamily. | 2004-01 |
|
| Metabolic flux analysis of pykF gene knockout Escherichia coli based on 13C-labeling experiments together with measurements of enzyme activities and intracellular metabolite concentrations. | 2004-01 |
|
| Human aldehyde dehydrogenase 3A1 (ALDH3A1): biochemical characterization and immunohistochemical localization in the cornea. | 2003-12-15 |
|
| [Kinetic parameters of androgen receptor complexes and the activities of the glycolysis and oxidative pentose phosphate pathway key enzymes in rat testis cytosol after whole body 60-min exposure to high frequency electromagnetic field (39.5 Ghz)]. | 2003-12-09 |
|
| Coenzyme specificity of enzymes in the oxidative pentose phosphate pathway of Gluconobacter oxydans. | 2003-12 |
|
| Molecular cloning and characterization of rice 6-phosphogluconate dehydrogenase gene that is up-regulated by salt stress. | 2003-12 |
|
| Significance of phosphoglucose isomerase for the shift between heterolactic and mannitol fermentation of fructose by Oenococcus oeni. | 2003-12 |
|
| Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus. | 2003-11-21 |
|
| Metabolic engineering of pentose phosphate pathway in Ralstoniaeutropha for enhanced biosynthesis of poly-beta-hydroxybutyrate. | 2003-10-04 |
|
| [Pathomechanism of hyperlipoproteinemia in chronic renal failure]. | 2003-10 |
|
| Increased activity of glycerol 3-phosphate dehydrogenase and other lipogenic enzymes in human bladder cancer. | 2003-10 |
|
| Protein S-thiolation targets glycolysis and protein synthesis in response to oxidative stress in the yeast Saccharomyces cerevisiae. | 2003-09-01 |
|
| Synthesis and biological evaluation of substrate-based inhibitors of 6-phosphogluconate dehydrogenase as potential drugs against African trypanosomiasis. | 2003-07-17 |
|
| From genome to enzyme: analysis of key glycolytic and oxidative pentose-phosphate pathway enzymes in the cyanobacterium Synechocystis sp. PCC 6803. | 2003-07 |
|
| Metabolic zonation in teleost gastrointestinal tract. Effects of fasting and cortisol in tilapia. | 2003-07 |
|
| The age-related inverse relationship between ob and lipogenic enzymes genes expression in rat white adipose tissue. | 2003-04 |
|
| Up-regulation of glutathione metabolism and changes in redox status involved in adaptation of reed (Phragmites communis) ecotypes to drought-prone and saline habitats. | 2003-03 |
|
| The treatment of Plasmodium falciparum-infected erythrocytes with chloroquine leads to accumulation of ferriprotoporphyrin IX bound to particular parasite proteins and to the inhibition of the parasite's 6-phosphogluconate dehydrogenase. | 2003-03 |
|
| Synthesis of (R)-2-methyl-4-deoxy and (R)-2-methyl-4,5-dideoxy analogues of 6-phosphogluconate as potential inhibitors of 6-phosphogluconate dehydrogenase. | 2003-02-07 |
|
| Purification of 6-phosphogluconate dehydrogenase from parsley (Petroselinum hortense) leaves and investigation of some kinetic properties. | 2003-02 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:25:51 GMT 2025
by
admin
on
Mon Mar 31 18:25:51 GMT 2025
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| Record UNII |
W31WK7B8U0
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| Record Status |
Validated (UNII)
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| Record Version |
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W31WK7B8U0
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91493
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213-069-9
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DTXSID00872623
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DB02076
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6-PHOSPHOGLUCONIC ACID
Created by
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