U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 591 - 600 of 1065 results

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Possibly Marketed Outside US
Source:
NCT01930331: Phase 4 Interventional Completed Plasmodium Falciparum
(2014)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Naphthoquine is an antimalarial drug first synthesized in China in 1986 but which was not developed for clinical use until the late 1990s. This drug now is used in combination for treatment of Plasmodium Falciparum and Malaria. The use of anti-malarial drug combinations with artemisinin or with one of its derivatives is now widely recommended to overcome drug resistance in falciparum as well as vivax malaria. The fixed oral dose artemisinin-naphthoquine combination (ANQ, ARCO™) is a newer artemisinin-based combination (ACT) therapy undergoing clinical assessment.
Vinburnine is a nutritional product, a peripheral vasodilator with cerebral activities that also act as a cerebral metabolic stimulant and appears to be able to relax the smooth muscle cells within the walls of blood vessels. (+/-)-Eburnamonine is the racemate of the alkaloid Vinburnine. Dextrorotatory, levorotatory, and racemic forms of eburnamonine exist in nature. The (-)-form, also known as vincamone (isolated from Vinca minor), is a drug that possesses a stimulating activity for muscle and is used as cerebrotonic, whereas both enantiomers have hypotensive effects.
Status:
Possibly Marketed Outside US
Source:
Canada:FERROUS PHOSPHATE
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Ferrous phosphate is used for killing moss and slug pelletes.
Status:
Possibly Marketed Outside US
Source:
CFR:21 CFR 310.548
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Silver phosphate or silver orthophosphate is a chemical compound consists of silver and phosphate. Silver phosphate has different applications, in photocatalysis to remove the antibiotic from water, in silver staining of biological materials, in photography.
Sodium glycerol 2-phosphate (Disodium beta-glycerophosphate) is used for the preparation of thermo-sensitive chitosan hydrogen as a scaffold to construct tissue engineered injectable nucleus pulposus (NP). Since Sodium glycerol 2-phosphate (6 g/day) reduced the lithogenic index of bile in human subjects with cholesterol gallstones in a short-term study and facilitated dissolution of cholesterol gallstones in mice, Sodium glycerol 2-phosphate may have potential to help dissolve cholesterol gallstones in man. Sodium glycerol 2-phosphate is an alkaline phosphate inhibitor. Sodium β-glycerophosphate pentahydrate is used as a phosphatase inhibitor. It promotes bone matrix mineralization while delivering to osteoblasts by providing a source of phosphate ions. It is used in the development of hydrogels and scaffolds, which finds applications in tissue engineering and cell growth. It is used as an additive in isolation mediums by providing phosphate ions to isolate. It is utilized to promote mineralization in vitro by modulating bone cell metabolic activity.
Status:
Possibly Marketed Outside US
Source:
CFR:21 CFR 310.547
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

QUININE PHOSPHATE, a salt of quinine, was formerly used for the treatment of malaria.
Status:

Class (Stereo):
CHEMICAL (RACEMIC)

CLOMACRAN, a non-phenothiazine tricyclic compound, is an antipsychotic drug.
mixture
Status:
Investigational
Source:
NCT00293878: Phase 2 Interventional Completed Hypercholesterolemia
(2005)
Source URL:

Class:
MIXTURE