CLOMACRAN PHOSPHATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H21ClN2.H3O4P
Molecular Weight	398.821
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OP(O)(O)=O.CN(C)CCCC1C2=C(NC3=C1C=C(Cl)C=C3)C=CC=C2

InChI

InChIKey=SKKDWRIEPIZVOR-UHFFFAOYSA-N

InChI=1S/C18H21ClN2.H3O4P/c1-21(2)11-5-7-14-15-6-3-4-8-17(15)20-18-10-9-13(19)12-16(14)18;1-5(2,3)4/h3-4,6,8-10,12,14,20H,5,7,11H2,1-2H3;(H3,1,2,3,4)

HIDE SMILES / InChI

Molecular Formula	H3O4P
Molecular Weight	97.9952
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C18H21ClN2
Molecular Weight	300.826
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.drugfuture.com/chemdata/clomacran.html | https://www.ncbi.nlm.nih.gov/pubmed/17419

CLOMACRAN, a non-phenothiazine tricyclic compound, is an antipsychotic drug.

CNS Activity

Approval Year

PubMed

Title	Date	PubMed
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.	2011 Jul 14	21599003
Chlorpromazine versus every other antipsychotic for schizophrenia: a systematic review and meta-analysis challenging the dogma of equal efficacy of antipsychotic drugs.	2014 Jul	24766970

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:06:22 GMT 2023` Edited by `admin` on `Fri Dec 15 15:06:22 GMT 2023`
Record UNII	7A1GN6M31H
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CLOMACRAN PHOSPHATE

Official Name

English

DEVRYL

Brand Name

English

Clomacran phosphate [WHO-DD]

Common Name

English

OLAXIN

Brand Name

English

SKF-14336

Code

English

CLOMACRAN PHOSPHATE [USAN]

Common Name

English

2-Chloro-9-[3-(dimethylamino)propyl]acridan phosphate (1:1)

Systematic Name

English

SK&F-14336

Code

English

9-ACRIDINEPROPANAMINE, 2-CHLORO-9,10-DIHYDRO-N,N-DIMETHYL-, PHOSPHATE (1:1)

Systematic Name

English

CLOMACRAN PHOSPHATE [MI]

Common Name

English

SK&F 14336

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29756