U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 51 - 60 of 190 results

Status:
Investigational
Source:
INN:clibucaine
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Clibucaine is a piperidine derivative possessing local anesthetic properties and used in the clinic as a local anesthetic in the 1980s.
Status:
Investigational
Source:
INN:edronocaine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:ketocaine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

KETOCAINE is a local anesthetic.
Status:
Investigational
Source:
INN:clormecaine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Clormecaine is a local anesthetic drug.
Status:
Investigational
Source:
INN:hydroxytetracaine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Hydroxytetracaine (also known as oxyamethocaine or hydroxamethocaine) was used as a local anesthetic. Information about the current use of this drug is not available.
Status:
Investigational
Source:
Physiol Res. Nov 2019;68(Suppl 1):S65-S74.: Not Applicable Human clinical trial Completed Low Back Pain
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Trimecaine is an amide series local anesthetic with antiarrhythmic activity. It was shown to be capable of eliminating the flutter of atria in dogs simulated by an electric stimulation of the myocardium and atrial fibrillation in cats induced with aconitin and precludes ventricular fibrillation in rats arising due to intoxication with calcium chloride. Trimecaine noticeably mitigates the toxic effect of strophanthin. While depressing the automatism of the sinoatrial node the drug does not affect the conduction function. The combination of epidural trimecaine with morphine after a major urological surgery provides a superior analgesia with fewer side effects when compared to epidurally delivered bupivacaine with fentanyl.
Status:
Investigational
Source:
INN:ketocainol
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

KETOCAINOL is an antiarrhythmic agent, anaesthetic.
Status:
Investigational
Source:
INN:fexicaine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

FEXICAINE, a phenoxyacetic acid derivative, is a vasodilator and local anesthetic.
Status:
Investigational
Source:
INN:erocainide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT02674191: Not Applicable Interventional Unknown status Orthodontic Anchorage Procedures
(2016)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Dexivacaine is a local anesthetic drug that has minimal and non-significant side effects.