U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 551 - 560 of 9908 results

Status:
Investigational
Source:
USAN:LIOTHYRONINE I 125 [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

A radioconjugate of synthetic active thyroid hormone, liothyronine (T3), labeled with Iodine 125. Liothyronine involves many important metabolic functions and is essential to the proper development and differentiation of all cells. I-125 liothyronine may be used in radiotherapy in thyroid cancers. It was used for the thyroxine T4 determination in serum by competitive protein-binding analysis.
Status:
Investigational
Source:
INN:diftalone [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Diftalone is a symmetrical tetracyclic compound with anti-inflammatory and antipyretic activities. The anti-inflammatory potency of diftalone is greater than that of aspirin, approximately equal to that of phenylbutazone, but lower than that of indomethacin. Diftalone exhibited limited but statistically significant antipyretic activities. It less potent than aspirin or phenylbutazone. Diftalone seems to be an effective and safe anti-inflammatory agent in the treatment of rheumatoid arthritis. It demonstrated the same activity as indomethacin and phenylbutazone. However, because of hepatotoxicity and carcinogenicity (hepatoma) in preclinical studies and hemotoxicity and gastrointestinal adverse effects in humans, diftalone was withdrawn by its manufacturer.
Status:
Investigational
Source:
USAN:DIOTYROSINE I 125 [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Diotyrosine I 125 is the diagnostic aid.
Status:
Investigational
Source:
INN:medazomide [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Medazomide (medazonamide) is an antitussive drug.
Status:
Investigational
Source:
NCT00162799: Phase 2 Interventional Completed Insulin Resistance
(2002)
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
NCT01316237: Phase 1 Interventional Completed Hepatitis C, Chronic
(2011)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
NCT03560323: Phase 1 Interventional Recruiting Heart Failure
(2019)
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
Invest New Drugs. Feb 1990;8(1):113-9.: Phase 2 Human clinical trial Completed Soft Tissue Neoplasms
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Designated
Source:
FDA ORPHAN DRUG:617017
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)