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Search results for amphotericin root_names_stdName in Standardized Name (approximate match)
Status:
Investigational
Source:
NCT02290951: Phase 1 Interventional Active, not recruiting Non-Hodgkin Lymphoma
(2015)
Source URL:
Class:
PROTEIN
Status:
Investigational
Source:
NCT02528903: Phase 1 Interventional Completed Healthy Volunteer
(2015)
Source URL:
Class:
PROTEIN
Status:
Investigational
Source:
NCT03736772: Phase 1 Interventional Completed Healthy
(2018)
Source URL:
Class:
PROTEIN
Status:
Investigational
Source:
NCT01195948: Phase 1/Phase 2 Interventional Completed Uveitis
(2010)
Source URL:
Class:
PROTEIN
Status:
Investigational
Source:
NCT02888106: Phase 2 Interventional Completed Chronic Viral Hepatitis B With Delta-agent
(2016)
Source URL:
Class:
PROTEIN
HBVPRES/2-48CONS-MYR (known as Bulevirtide or Myrcludex B) was developed as an agent bind and inactivate the hepatocyte surface protein sodium taurocholate cotransporting polypeptide (SLC10A1 or NTCP). By blocking NTCP, the drug misdirects hepatitis B virus (HBV) and co-infecting hepatitis D virus (HDV) to an unproductive pathway and thereby prevents infection of the cell. Because NTCP is involved in the bile acid transport cycle, the blockade of this target by myrcludex B can potentially be used for the treatment of various metabolic and inflammatory diseases. Myrcludex B is going to participate in phase 3 trial for patients with chronic hepatitis D, however, the study is not yet recruited. The drug successfully completed phase II clinical trial for the patients with chronic hepatitis B and D. In addition, myrcludex B has been studied during preclinical research as a potential treatment of dyslipidemias, non-alcoholic steatohepatitis; primary biliary cirrhosis.
Status:
Investigational
Source:
NCT02501577: Not Applicable Interventional Unknown status Intubation; Difficult
(2015)
Source URL:
Class:
PROTEIN
Status:
Investigational
Source:
NCT01487915: Phase 2 Interventional Unknown status Advanced Urothelial Carcinoma
(2010)
Source URL:
Class:
PROTEIN
Status:
Investigational
Source:
NCT02545504: Phase 3 Interventional Completed Gastric Adenocarcinoma
(2015)
Source URL:
Class:
PROTEIN
Status:
Investigational
Source:
INN:exbivirumab [INN]
Source URL:
Class:
PROTEIN
Class:
PROTEIN
