U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Tue Apr 01 19:50:34 GMT 2025
Edited
by admin
on Tue Apr 01 19:50:34 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
D99LD4BK0S
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PEPTIDE B27PD
Common Name English
OPTIQUEL
Preferred Name English
B-27PD
Code English
AMINO ACIDS 125-138 OF HLA-B
Common Name English
ALNEDLSSWTAADT
Common Name English
B27PD
Code English
L-THREONINE, L-ALANYL-L-LEUCYL-L-ASPARAGINYL-L-.ALPHA.-GLUTAMYL-L-.ALPHA.-ASPARTYL-L-LEUCYL-L-SERYL-L-SERYL-L-TRYPTOPHYL-L-THREONYL-L-ALANYL-L-ALANYL-L-.ALPHA.-ASPARTYL-
Systematic Name English
Code System Code Type Description
SMS_ID
300000019352
Created by admin on Tue Apr 01 19:50:34 GMT 2025 , Edited by admin on Tue Apr 01 19:50:34 GMT 2025
PRIMARY
CAS
160387-12-2
Created by admin on Tue Apr 01 19:50:34 GMT 2025 , Edited by admin on Tue Apr 01 19:50:34 GMT 2025
PRIMARY
FDA UNII
D99LD4BK0S
Created by admin on Tue Apr 01 19:50:34 GMT 2025 , Edited by admin on Tue Apr 01 19:50:34 GMT 2025
PRIMARY
Related Record Type Details
TARGET->MIMETIC
A small peptide that has been shown to mimic the retinal S-antigen, the offending protein antigen responsible for the ocular inflammation. Intraocular uveitis appears to result from an autoimmune reaction to antigens in the eye, specifically the S-antigen and the interphotoreceptor-retinoid-binding-protein (IRBP). OptiquelT has been designed to down regulate this undesired autoimmune response by inducing a specific immune tolerance to the retinal S-antigen.
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL