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Restrict the search for
beta carotene
to a specific field?
Class (Stereo):
CHEMICAL (UNKNOWN)
Dioxifedrine is the putative metabolite of 3,4-methylenedioxymethamphetamine. It is the sympathomimetic agent and beta-2 -adrenergic agonist with bronchodilator activity. Dioxifedrine selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle. In stimulatory studies dioxifedrine increased locomotor activity from 15 to 30 min following the drug administration. Following intracerebroventricular injection dioxifedrine rapidly reduced blood pressure and heart rate.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Nylestriol is a synthetic estrogen which is marketed in China under the brand name Wei Ni An. Nylestriol can be used as an effective and acceptable estrogen replacement therapy for postmenopausal women. It was found to be effective, safe and convenient in treating postmenopausal osteoporosis.
Status:
Investigational
Source:
NCT03593226: Phase 1/Phase 2 Interventional Completed Superficial, Palpable, Unresectable/Metastatic Solid Tumour
(2018)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
INN:frespaciguat [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
NCT01847521: Phase 2 Interventional Completed Autism Spectrum Disorders
(2011)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and cancer. Luteolin possesses a variety of pharmacological activities, including antioxidant, anti-inflammatory, antimicrobial and anticancer activities. Numerous studies have shown that luteolin possesses beneficial neuroprotective effects both in vitro and in vivo.
Status:
Investigational
Source:
NCT01382069: Phase 1 Interventional Completed Healthy Men
(2012)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
INN:vemtoberant [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Class (Stereo):
CHEMICAL (ABSOLUTE)
Oxisopred is a synthetic corticosteroid that has never been marketed. Information about the current use of this compound is not available.
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Investigational
Source:
NCT01716910: Early Phase 1 Interventional Completed Synbiotics
(2011)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
