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Restrict the search for
tamoxifen
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Status:
Investigational
Source:
INN:afimoxifene [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Hydroxytamoxifen (Afimoxifene) is an active metabolite of tamoxifen exerting estrogen receptor modulatory function. In addition, hydroxytamoxifen binds to regulates transcriptional activity of the estrogen-related receptor gamma. ASCEND Therapeutics, Inc. was developing TamoGel (4-hydroxytamoxifen gel) for a variety of estrogen-dependent conditions, including breast cancer, cyclic breast pain and gynecomastia.
