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Restrict the search for
halobetasol propionate
to a specific field?
Status:
Possibly Marketed Outside US
Source:
21 CFR 352
(2015)
Source URL:
First approved in 2012
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
21 CFR 352
(2012)
Source URL:
First approved in 2012
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(2012)
Source URL:
First approved in 2012
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M006
(2013)
Source URL:
First approved in 2012
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
4-Carvomenthenol (Terpinen-4-ol) is an anti-inflammatory and antimicrobial agent. 4-Carvomenthenol is a fragrance ingredient used in decorative
cosmetics, fine fragrances, shampoos, toilet soaps and other toiletries as well as in non-cosmetic products such as household cleaners and detergents. Its use worldwide is in the region of 1–10
metric tonnes per annum.
The maximum skin level that results from the use of
4-carvementhenol in formulae that go into fine fragrances has
been reported to be 0.13%. 4-Carvomenthenol has been shown to have antiviral, antibacterial, antifungal, and insecticidal effects as well as antioxidant and anti-inflammatory activities. It is a putative anitcancer agent. 4-carvementhenol exerts its antitumor effects by triggering caspase-dependent apoptosis in human melanoma cells or by inducing necrotic cell death and cell-cycle arrest in mouse mesothelioma and melanomacell lines without affecting normal cells. Caspase-dependent mitochondrial dysfunction is the mechanism of terpinen-4-ol-induced apoptosis in nonsmall lung cancer cells. Down-regulation of Bcl-2, XIAP and survivin suggests that ter-pinen-4-ol increases the susceptibility of NSCLC cells toapoptosis induction. Notably, the ability of terpinen-4-ol to induce apoptosis in NSCLC cells is p53-dependent. It has also been shown that the growth of s.c. xenograft tumors was remarkably inhibited by intratumoral injection of terpinen-4-ol, indicating that the agent also has potential for clinical anticancer activity.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333E
(2012)
Source URL:
First approved in 2012
Source:
21 CFR 333E
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
21 CFR 350
(2020)
Source URL:
First approved in 2012
Source:
21 CFR 333E
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Benzyl acetate is used as a fragrance ingredient and occurs in different plants and fruits, e.g., jasmine, apple, tea, plum, wine grape. It possesses a sweet and pleasant aroma, owing to which, it finds applications in personal hygiene and health care products.
Status:
Possibly Marketed Outside US
Source:
M006
(2020)
Source URL:
First approved in 2011
Source:
21 CFR 348
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Possibly Marketed Outside US
Source:
21 CFR 352
(2011)
Source URL:
First approved in 2011
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
21 CFR 348
(2011)
Source URL:
First approved in 2011
Source:
21 CFR 348
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Citronellal is one of the main constituents of the essential oil from lemongrass (Cymbopogon). Citronellal is a major isolate from Cymbopogon plants, lemon-scented gum, and lemon-scented tea tree. Citronellal is a well-known plant-derived mosquito repellent. In addition, citronellal is very effective repellent against Sitophilus zeamais. Citronellal showed anticandidal activity against C. albicans and non-albicans species of Candida. Citronellal is effective as an analgesic compound in various rodent pain models, with its action probably mediated by the inhibition of peripheral mediators as well as central inhibitory mechanisms that could be related to its strong antioxidant effect observed in vitro.
Status:
Possibly Marketed Outside US
Source:
M017
(2011)
Source URL:
First approved in 2011
Source:
M017
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
