Thiosalicylic acid is an analgesic and anti-inflammatory agent. It is used (in form of sodium salt) to relieve symptoms of acute gout, painful musculoskeletal conditions, osteoarthritis and rheumatic fever. The drug exerts its action by inhibiting prostaglandin synthesis. Thiosalicylic acid usage is associated with the risk of contact dermatitis.

Ortho-iodohippurate (also known IODOHIPPURATE) as is used for the determination of effective renal plasma flow. It is a halogen derivative of a compound normally found in human urine, and as the end product of a process of detoxification is synthesized in the body. This compound is nontoxic, when administrated intravenous. In patients with normally functioning kidneys, 85% of the ortho-iodohippurate may be found in the urine 30 minutes after intravenous injection. It is eliminated mainly by tubular secretion.