IODOHIPPURATE SODIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H7INO3.Na
Molecular Weight	327.051
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[O-]C(=O)CNC(=O)C1=CC=CC=C1I

InChI

InChIKey=XYITYKDGJLHYPW-UHFFFAOYSA-M

InChI=1S/C9H8INO3.Na/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13;/h1-4H,5H2,(H,11,14)(H,12,13);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.98976928
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C9H7INO3
Molecular Weight	304.0613
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: DOI: 10.1111/j.1464-410X.1935.tb11294.x Retrived from http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.1935.tb11294.x/abstract

Ortho-iodohippurate (also known IODOHIPPURATE) as is used for the determination of effective renal plasma flow. It is a halogen derivative of a compound normally found in human urine, and as the end product of a process of detoxification is synthesized in the body. This compound is nontoxic, when administrated intravenous. In patients with normally functioning kidneys, 85% of the ortho-iodohippurate may be found in the urine 30 minutes after intravenous injection. It is eliminated mainly by tubular secretion.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Renal plasma flow 3 Sources: DOI: 10.1111/j.1464-410X.1935.tb11294.x	Diagnostic		Natural Metabolite	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Availability and use of essential medicines in China: manufacturing, supply, and prescribing in Shandong and Gansu provinces.	2010-07-17	20637116
Glomerular filtration rate measured by (51)Cr-EDTA clearance: Evaluation of captopril-induced changes in hypertensive patients with and without renal artery stenosis.	2010-06	20613937
Synthesis and mass spectroscopy kinetics of a novel ternary copper(II) complex with cytotoxic activity against cancer cells.	2007-04	17292964
Validation of neutron activation as a novel method to determine glomerular filtration rate.	2007	17940340
Idiopathic neurohypophysial diabetes insipidus: reversibility of structural and functional renal abnormalities after treatment.	2005-07-22	16033721
Effects of contrast media on renal function in patients with cirrhosis: a prospective study.	2004-09	15349903
Transport of 99mTc-MAG3 via rat renal organic anion transporter 1.	2004-01	14734677
Simplified methods for estimation of 99mTc-pentetate and 131I-orthoiodohippurate plasma clearance in dogs and cats.	2001-05-31	11380028

Patents

Sample Use Guides

In Vivo Use Guide

in rats: 2 g/kg bw

Route of Administration: Intravenous

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:53:59 GMT 2025` Edited by `admin` on `Mon Mar 31 17:53:59 GMT 2025`
Record UNII	UVJ3W62NGI
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-63351

Preferred Name

English

IODOHIPPURATE SODIUM

Systematic Name

English

HIPPODIN

Common Name

English

O-IODOHIPPURATE SODIUM [MI]

Common Name

English

SODIUM IODOHIPPURATE

Systematic Name

English

N-(2-IODOBENZOYL)GLYCINE MONOSODIUM SALT

Common Name

English

SODIUM O-IODOHIPPURATE

Common Name

English

SODIUM 2-IODOHIPPURATE

Systematic Name

English

HIPPURAN

Common Name

English

Iodohippurate sodium [WHO-DD]

Common Name

English

Code System Code Type Description

FDA UNII

UVJ3W62NGI