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Details

Stereochemistry ACHIRAL
Molecular Formula C9H7INO3.Na.2H2O
Molecular Weight 363.0816
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IODOHIPPURATE SODIUM DIHYDRATE

SMILES

O.O.[Na+].[O-]C(=O)CNC(=O)C1=CC=CC=C1I

InChI

InChIKey=DPJNBVXUJNOEQS-UHFFFAOYSA-M
InChI=1S/C9H8INO3.Na.2H2O/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13;;;/h1-4H,5H2,(H,11,14)(H,12,13);;2*1H2/q;+1;;/p-1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C9H7INO3
Molecular Weight 304.0613
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Ortho-iodohippurate (also known IODOHIPPURATE) as is used for the determination of effective renal plasma flow. It is a halogen derivative of a compound normally found in human urine, and as the end product of a process of detoxification is synthesized in the body. This compound is nontoxic, when administrated intravenous. In patients with normally functioning kidneys, 85% of the ortho-iodohippurate may be found in the urine 30 minutes after intravenous injection. It is eliminated mainly by tubular secretion.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Sources: DOI: 10.1111/j.1464-410X.1935.tb11294.x
Diagnostic
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Availability and use of essential medicines in China: manufacturing, supply, and prescribing in Shandong and Gansu provinces.
2010-07-17
Glomerular filtration rate measured by (51)Cr-EDTA clearance: Evaluation of captopril-induced changes in hypertensive patients with and without renal artery stenosis.
2010-06
Synthesis and mass spectroscopy kinetics of a novel ternary copper(II) complex with cytotoxic activity against cancer cells.
2007-04
Validation of neutron activation as a novel method to determine glomerular filtration rate.
2007
Idiopathic neurohypophysial diabetes insipidus: reversibility of structural and functional renal abnormalities after treatment.
2005-07-22
Effects of contrast media on renal function in patients with cirrhosis: a prospective study.
2004-09
Transport of 99mTc-MAG3 via rat renal organic anion transporter 1.
2004-01
Simplified methods for estimation of 99mTc-pentetate and 131I-orthoiodohippurate plasma clearance in dogs and cats.
2001-05-31
Patents

Patents

Sample Use Guides

In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 23:39:55 GMT 2025
Edited
by admin
on Mon Mar 31 23:39:55 GMT 2025
Record UNII
911OMR805P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HIPPURAN HYDRATE
Preferred Name English
IODOHIPPURATE SODIUM DIHYDRATE
Systematic Name English
O-IODOHIPPURATE SODIUM DIHYDRATE [MI]
Common Name English
GLYCINE, N-(2-IODOBENZOYL)-, MONOSODIUM SALT, DIHYDRATE
Systematic Name English
Code System Code Type Description
PUBCHEM
72941473
Created by admin on Mon Mar 31 23:39:55 GMT 2025 , Edited by admin on Mon Mar 31 23:39:55 GMT 2025
PRIMARY
CAS
5990-94-3
Created by admin on Mon Mar 31 23:39:55 GMT 2025 , Edited by admin on Mon Mar 31 23:39:55 GMT 2025
PRIMARY
FDA UNII
911OMR805P
Created by admin on Mon Mar 31 23:39:55 GMT 2025 , Edited by admin on Mon Mar 31 23:39:55 GMT 2025
PRIMARY
MERCK INDEX
m6347
Created by admin on Mon Mar 31 23:39:55 GMT 2025 , Edited by admin on Mon Mar 31 23:39:55 GMT 2025
PRIMARY Merck Index
Related Record Type Details
ANHYDROUS->SOLVATE