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Details

Stereochemistry ACHIRAL
Molecular Formula C9H7INO3.Na.2H2O
Molecular Weight 363.0816
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IODOHIPPURATE SODIUM DIHYDRATE

SMILES

O.O.[Na+].[O-]C(=O)CNC(=O)C1=CC=CC=C1I

InChI

InChIKey=DPJNBVXUJNOEQS-UHFFFAOYSA-M
InChI=1S/C9H8INO3.Na.2H2O/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13;;;/h1-4H,5H2,(H,11,14)(H,12,13);;2*1H2/q;+1;;/p-1

HIDE SMILES / InChI

Molecular Formula C9H7INO3
Molecular Weight 304.0613
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Ortho-iodohippurate (also known IODOHIPPURATE) as is used for the determination of effective renal plasma flow. It is a halogen derivative of a compound normally found in human urine, and as the end product of a process of detoxification is synthesized in the body. This compound is nontoxic, when administrated intravenous. In patients with normally functioning kidneys, 85% of the ortho-iodohippurate may be found in the urine 30 minutes after intravenous injection. It is eliminated mainly by tubular secretion.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Sources: DOI: 10.1111/j.1464-410X.1935.tb11294.x
Diagnostic
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Idiopathic neurohypophysial diabetes insipidus: reversibility of structural and functional renal abnormalities after treatment.
2004 Nov-Dec
Validation of neutron activation as a novel method to determine glomerular filtration rate.
2007
Synthesis and mass spectroscopy kinetics of a novel ternary copper(II) complex with cytotoxic activity against cancer cells.
2007 Apr
Availability and use of essential medicines in China: manufacturing, supply, and prescribing in Shandong and Gansu provinces.
2010 Jul 17
Glomerular filtration rate measured by (51)Cr-EDTA clearance: Evaluation of captopril-induced changes in hypertensive patients with and without renal artery stenosis.
2010 Jun
Patents

Patents

Sample Use Guides

In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:09:14 GMT 2023
Edited
by admin
on Sat Dec 16 11:09:14 GMT 2023
Record UNII
911OMR805P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IODOHIPPURATE SODIUM DIHYDRATE
Systematic Name English
HIPPURAN HYDRATE
Common Name English
O-IODOHIPPURATE SODIUM DIHYDRATE [MI]
Common Name English
GLYCINE, N-(2-IODOBENZOYL)-, MONOSODIUM SALT, DIHYDRATE
Systematic Name English
Code System Code Type Description
PUBCHEM
72941473
Created by admin on Sat Dec 16 11:09:14 GMT 2023 , Edited by admin on Sat Dec 16 11:09:14 GMT 2023
PRIMARY
CAS
5990-94-3
Created by admin on Sat Dec 16 11:09:14 GMT 2023 , Edited by admin on Sat Dec 16 11:09:14 GMT 2023
PRIMARY
FDA UNII
911OMR805P
Created by admin on Sat Dec 16 11:09:14 GMT 2023 , Edited by admin on Sat Dec 16 11:09:14 GMT 2023
PRIMARY
MERCK INDEX
m6347
Created by admin on Sat Dec 16 11:09:14 GMT 2023 , Edited by admin on Sat Dec 16 11:09:14 GMT 2023
PRIMARY Merck Index
Related Record Type Details
ANHYDROUS->SOLVATE