U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 401 - 410 of 31825 results

Status:
Investigational
Source:
INN:ioxabrolic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Ioxabrolic Acid is triiodobenzoic acid derivative and iodine-containing contrast media
Status:
Investigational
Source:
INN:iomorinic acid
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Iomorinic Acid is triiodobenzamide derivative patented by Lentia G.m.b.H. as a radiographic contrast medium for liver imaging.
Status:
Investigational
Source:
INN:indorenate [INN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Indorenate (TR3369, INDO) is a serotonin-like compound with high affinity for 5- HT1A receptors and a lower affinity for 5-HT1C and 5-HT1B receptors. Indorenate possesses antihypertensive and anxiolytic activity in animal behaviour tests. Similar to other serotonin receptor agonists, Indorenate also has anorectic activity; this effect was blocked by the administration of the 5-HT2A/2C receptor antagonists cinanserin, cyproheptadine, metergoline and methysergide. A unpublished clinical trial confirmed its antihypertensive activity in men.
Status:
Investigational
Source:
JAN:ACORAMIDIS HYDROCHLORIDE [JAN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:fenamifuril
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Fenamifuril is an antiinflammatory and antirheumatic agent.
Status:
Investigational
Source:
INN:nifursol
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Nifursol is an antibiotic of the nitrofuran class which inhibits the growth of the protozoa Histomonas meleagridis but is non-lethal. Although previously approved as a prophylactic feed additive for turkeys, the European Union has since banned Nifursol use in agricultural operations.
Status:
Investigational
Source:
INN:biclofibrate
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Biclofibrate was investigated as an antilipidemic agent.
Status:
Investigational
Source:
NCT03022799: Phase 1 Interventional Completed Parkinson's Disease
(2016)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:clamidoxic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Clamidoxic acid is a derivative of phenoxyacetic acid developed in the late 1950s by Smith and Nephew Research Ltd. Clamidoxic acid has been shown to have anti-inflammatory activity and low toxicity in animal tests. The compound was investigated in the clinical trials in patients suffering from rheumatoid arthritis and painful uncomplicated osteoarthritis of the hip, however, no further clinical development was reported.
Status:
Investigational
Source:
INN:vinpoline
Source URL:

Class (Stereo):
CHEMICAL (EPIMERIC)

Vinpoline was studied as a central stimulant. Information about the further development of this agent is not available.