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Restrict the search for
isosorbide dinitrate
to a specific field?
Status:
US Previously Marketed
Source:
ISMOTIC by ALCON
(1974)
Source URL:
First approved in 1974
Source:
ISMOTIC by ALCON
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Isosorbide is an effective hyperosmotic agent which can be administered orally without gastrointestinal irritation. It is absorbed quantitatively and more than 95% of the administered dose is excreted unchanged in the urine. Oral administration of a 50% solution to rabbits or man results in prompt increases in osmolarity of the serum and profound decreases in intraocular pressure. The drug proves useful in acute primary and secondary glaucomas, and as preoperative medication for various surgical procedures including cataract extraction, retinal detachment, corneal transplant, and glaucoma operations.
Status:
Possibly Marketed Outside US
First approved in 2021
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Cupric nitrate (Copper(II) nitrate) is an inorganic compound that forms a blue crystalline solid. Copper(II) nitrate finds a variety of applications, the main one being its conversion to copper(II) oxide, which is used as catalyst for a variety of processes in organic chemistry. Its solutions are used in textiles and polishing agents for other metals. Copper nitrates are found in some pyrotechnics. It is often used in school laboratories to demonstrate chemical voltaic cell reactions. Strong oxidizing agent.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(2020)
Source URL:
First approved in 2020
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Clonitrate (chloroglyceryl dinitrate) is a derivative of nitroglycerin. The compound is identical with glycerol trinitrate with the exception of the replacement of the nitrate radical on the first carbon atom by an atom of chlorine. Clonitrate is equipotent with glycerine trinitrate in increasing coronary flow in Langendorff rabbit heart and appears to evoke a lesser degree of depressor response. In the 1960s, clonitrate was used in the clinics a vasodilator for the treatment of angina pectoris.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(2020)
Source URL:
First approved in 2020
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Possibly Marketed Outside US
Source:
21 CFR 352
(2018)
Source URL:
First approved in 2017
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Possibly Marketed Outside US
Source:
NDA020508
(2012)
Source URL:
First approved in 2012
Source:
NDA020508
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M005
(2019)
Source URL:
First approved in 2003
Source:
21 CFR 333D
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
DIMETHYL ISOSORBIDE is an inactive component of VANOS® Cream indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients 12 years of age or older.
Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (ACHIRAL)
Thiamine Disulfide Nitrate is a vitamin B1 derivative. It is used as a component of vitamin complexes for the treatment of neurological and other disorders
Status:
Possibly Marketed Outside US
Source:
Solcogyn
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Zinc nitrate is a colorless crystalline solid. It is used as a catalyst in the manufacture of other chemicals, in medicine, and in dyes, also as a fertilizer which helps plant growth and disease resistance.
Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (ACHIRAL)
Propatylnitrate (or propatyl nitrate), a coronary vasodilator that has been studied for the relief of acute attacks of angina pectoris. However, was revealed that this drug didn’t abolish or diminish the frequency of attacks of angina pectoris.
