Clonitrate (chloroglyceryl dinitrate) is a derivative of nitroglycerin. The compound is identical with glycerol trinitrate with the exception of the replacement of the nitrate radical on the first carbon atom by an atom of chlorine. Clonitrate is equipotent with glycerine trinitrate in increasing coronary flow in Langendorff rabbit heart and appears to evoke a lesser degree of depressor response. In the 1960s, clonitrate was used in the clinics a vasodilator for the treatment of angina pectoris.