U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 3961 - 3970 of 4227 results

Sarcosine, also known as N-methylglycine, is a metabolite of glycine. It shares properties with both glycine and D-serine, though its effects are weaker. Sarcosine supplementation can be used to alleviate symptoms of depression and schizophrenia, or improve cognition. It is absorbed more reliably by the body than D-serine, which can also treat similar conditions. Sarcosine is being investigated for its connection to prostate cancer. It may be a biomarker for prostate cancer, which means that if sarcosine levels in the blood are higher than normal, it could be an indicator of prostate cancer. This doesn’t mean that sarcosine itself causes cancer. More research is needed to confirm this relationship. Sarcosine’s main mechanism involves inhibiting a transporter, called GlyT1, which takes up glycine and D-serine into cells. This increases the levels of glycine and D-serine in the body and increases their effects. Sarcosine, a glycine transporter type 1 inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site, potentiates NMDA receptor function. Sarcosine is an inhibitory glycine receptor agonist.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

FD&C Red 4 is a synthetic dye produced from petroleum. It is a red coloring pigment, soluble in water. This dye is FDA-approved for use in food, pharmaceuticals, cosmetics and medical devices. Cosmetics applications include: alcoholic perfumes, decorative cosmetics, toilet soap, syndet and liquid tensid products.
Aluminum Stearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid. In the pharmaceutical industry, it is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent. According to the FDA, aluminum stearate is considered safe for general or specific, limited use in food. Aluminum stearate is not classifiable as a human carcinogen (cancer-causing agent).
Aluminum Stearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid. In the pharmaceutical industry, it is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent. According to the FDA, aluminum stearate is considered safe for general or specific, limited use in food. Aluminum stearate is not classifiable as a human carcinogen (cancer-causing agent).
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (RACEMIC)

Calteridol is tetraazacyclododecane-1,4,7-triacetic acid derivative patented by Bracco and Dibra S.P.A.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Monostearyl fumarate (sodium stearyl fumarate) is a lubricant for use in tablet formulation, it can be used as a taste-masking agent in orally disintegrating tablets. It is a conditioning and stabilizing agent.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Lauroyl sarcosine is an ionic surfactant. Sodium salt of lauroyl sarcosine is widely used in the cosmetic industry in shampoos, body washes, facial washes, foundations, bath soaps, and detergents. Lauroyl sarcosine is used in noncoloring shampoos, bath soaps, and detergents. Besides its use in cosmetic industry, lauroyl sarcosinate is used in adhesives and as an additive in polymers (with a maximal concentration of 0.35% according to the FDA regulations).
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Glyceryl trielaidate (glycerol trielaidate, or trielaidin) is a triglyceride formed by esterification of the three hydroxy groups of glycerol with elaidic acid.

Showing 3961 - 3970 of 4227 results