SODIUM STEARYL FUMARATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H39O4.Na
Molecular Weight	390.5324
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].CCCCCCCCCCCCCCCCCCOC(=O)\C=C\C([O-])=O

InChI

InChIKey=STFSJTPVIIDAQX-LTRPLHCISA-M

InChI=1S/C22H40O4.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-26-22(25)19-18-21(23)24;/h18-19H,2-17,20H2,1H3,(H,23,24);/q;+1/p-1/b19-18+;

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C22H39O4
Molecular Weight	367.5427
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/30714850 | https://www.ncbi.nlm.nih.gov/pubmed/29432807 | https://www.ncbi.nlm.nih.gov/pubmed/18396020 | https://www.ncbi.nlm.nih.gov/pubmed/3735097 | http://www.thegoodscentscompany.com/data/rw1611261.html

Monostearyl fumarate (sodium stearyl fumarate) is a lubricant for use in tablet formulation, it can be used as a taste-masking agent in orally disintegrating tablets. It is a conditioning and stabilizing agent.

Approval Year

PubMed

Title	Date	PubMed
Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution.	1986 Jun	3735097
Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol.	2008 Aug	18396020

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 06:45:03 UTC 2023` Edited by `admin` on `Sat Dec 16 06:45:03 UTC 2023`
Record UNII	7CV7WJK4UI
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SODIUM STEARYL FUMARATE

Official Name

English

SODIUM STEARYL FUMARATE [II]

Common Name

English

SODIUM MONOSTEARYL FUMARATE

Systematic Name

English

SODIUM STEARYL FUMARATE [MART.]

Common Name

English

SODIUM STEARYL FUMARATE [FCC]

Common Name

English

SODIUM STEARYL FUMARATE [USP-RS]

Common Name

English

SODIUM STEARYL FUMARATE [INCI]

Common Name

English

FUMARIC ACID, OCTADECYL ESTER, SODIUM SALT

Common Name

English

SODIUM STEARYL FUMARATE [MI]

Common Name

English

SODIUM STEARYL FUMARATE [EP MONOGRAPH]

Common Name

English

SODIUM STEARYL FUMARATE [VANDF]

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 172.826