Sodium Stearyl Fumarate

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H39O4.Na
Molecular Weight	390.5324
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].CCCCCCCCCCCCCCCCCCOC(=O)\C=C\C([O-])=O

InChI

InChIKey=STFSJTPVIIDAQX-LTRPLHCISA-M

InChI=1S/C22H40O4.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-26-22(25)19-18-21(23)24;/h18-19H,2-17,20H2,1H3,(H,23,24);/q;+1/p-1/b19-18+;

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.98976928
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C22H39O4
Molecular Weight	367.5427
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/30714850 | https://www.ncbi.nlm.nih.gov/pubmed/29432807 | https://www.ncbi.nlm.nih.gov/pubmed/18396020 | https://www.ncbi.nlm.nih.gov/pubmed/3735097 | http://www.thegoodscentscompany.com/data/rw1611261.html

Monostearyl fumarate (sodium stearyl fumarate) is a lubricant for use in tablet formulation, it can be used as a taste-masking agent in orally disintegrating tablets. It is a conditioning and stabilizing agent.

Approval Year

PubMed

Title	Date	PubMed
Systematic evaluation of common lubricants for optimal use in tablet formulation.	2018-05-30	29432807
Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol.	2008-08	18396020
Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution.	1986-06	3735097

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:38:02 GMT 2025` Edited by `admin` on `Mon Mar 31 21:38:02 GMT 2025`
Record UNII	7CV7WJK4UI
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Sodium Stearyl Fumarate

Official Name

English

FUMARIC ACID, OCTADECYL ESTER, SODIUM SALT

Preferred Name

English

SODIUM STEARYL FUMARATE [II]

Common Name

English

SODIUM MONOSTEARYL FUMARATE

Systematic Name

English

SODIUM STEARYL FUMARATE [MART.]

Common Name

English

SODIUM STEARYL FUMARATE [FCC]

Common Name

English

SODIUM STEARYL FUMARATE [USP-RS]

Common Name

English

SODIUM STEARYL FUMARATE [MI]

Common Name

English

SODIUM STEARYL FUMARATE [EP MONOGRAPH]

Common Name

English

SODIUM STEARYL FUMARATE [VANDF]

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 172.826