Monostearyl fumarate

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H40O4
Molecular Weight	368.5506
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCCCCOC(=O)\C=C\C(O)=O

InChI

InChIKey=MHQJUHSHQGQVTM-VHEBQXMUSA-N

InChI=1S/C22H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-26-22(25)19-18-21(23)24/h18-19H,2-17,20H2,1H3,(H,23,24)/b19-18+

HIDE SMILES / InChI

Molecular Formula	C22H40O4
Molecular Weight	368.5506
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/30714850 | https://www.ncbi.nlm.nih.gov/pubmed/29432807 | https://www.ncbi.nlm.nih.gov/pubmed/18396020 | https://www.ncbi.nlm.nih.gov/pubmed/3735097 | http://www.thegoodscentscompany.com/data/rw1611261.html

Monostearyl fumarate (sodium stearyl fumarate) is a lubricant for use in tablet formulation, it can be used as a taste-masking agent in orally disintegrating tablets. It is a conditioning and stabilizing agent.

Approval Year

PubMed

Title	Date	PubMed
Systematic evaluation of common lubricants for optimal use in tablet formulation.	2018-05-30	29432807
Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol.	2008-08	18396020
Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution.	1986-06	3735097

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:20:07 GMT 2025` Edited by `admin` on `Mon Mar 31 20:20:07 GMT 2025`
Record UNII	X127TT7PK9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-Butenedioic acid (2E)-, monooctadecyl ester

Preferred Name

English

Monostearyl fumarate

Common Name

English

STEARYL FUMARIC ACID

Common Name

English

Octadecyl hydrogen fumarate

Systematic Name

English

2-Butenedioic acid (E)-, monooctadecyl ester

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID20169764