MONOSTEARYL FUMARATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H40O4
Molecular Weight	368.5506
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCCCCOC(=O)\C=C\C(O)=O

InChI

InChIKey=MHQJUHSHQGQVTM-VHEBQXMUSA-N

InChI=1S/C22H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-26-22(25)19-18-21(23)24/h18-19H,2-17,20H2,1H3,(H,23,24)/b19-18+

HIDE SMILES / InChI

Molecular Formula	C22H40O4
Molecular Weight	368.5506
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/30714850 | https://www.ncbi.nlm.nih.gov/pubmed/29432807 | https://www.ncbi.nlm.nih.gov/pubmed/18396020 | https://www.ncbi.nlm.nih.gov/pubmed/3735097 | http://www.thegoodscentscompany.com/data/rw1611261.html

Monostearyl fumarate (sodium stearyl fumarate) is a lubricant for use in tablet formulation, it can be used as a taste-masking agent in orally disintegrating tablets. It is a conditioning and stabilizing agent.

Approval Year

PubMed

Title	Date	PubMed
Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution.	1986 Jun	3735097
Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol.	2008 Aug	18396020
Systematic evaluation of common lubricants for optimal use in tablet formulation.	2018 May 30	29432807

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 21:31:14 GMT 2023` Edited by `admin` on `Fri Dec 15 21:31:14 GMT 2023`
Record UNII	X127TT7PK9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MONOSTEARYL FUMARATE

Systematic Name

English

2-BUTENEDIOIC ACID (2E)-, MONOOCTADECYL ESTER

Common Name

English

OCTADECYL HYDROGEN FUMARATE

Systematic Name

English

FUMARIC ACID, OCTADECYL ESTER

Common Name

English

FUMARIC ACID, MONOOCTADECYL ESTER

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID20169764