U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C15H28NO3.Na
Molecular Weight 293.3775
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM LAUROYL SARCOSINATE

SMILES

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

InChIKey=KSAVQLQVUXSOCR-UHFFFAOYSA-M
InChI=1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C15H28NO3
Molecular Weight 270.3877
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Lauroyl sarcosine is an ionic surfactant. Sodium salt of lauroyl sarcosine is widely used in the cosmetic industry in shampoos, body washes, facial washes, foundations, bath soaps, and detergents. Lauroyl sarcosine is used in noncoloring shampoos, bath soaps, and detergents. Besides its use in cosmetic industry, lauroyl sarcosinate is used in adhesives and as an additive in polymers (with a maximal concentration of 0.35% according to the FDA regulations).

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
CLODAN KIT

Approved Use

Clodan® (clobetasol propionate) Shampoo, 0.05% is a corticosteroid indicated for the treatment of moderate to severe scalp psoriasis in subjects 18 years of age and older.

Launch Date

1.40270397E12
PubMed

PubMed

TitleDatePubMed
Conformational behavior of N-acylamino acid oil and N-acylamino acid surfactant in aqueous solution.
2007
Extensive genomic diversity and selective conservation of virulence-determinants in enterohemorrhagic Escherichia coli strains of O157 and non-O157 serotypes.
2007
A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions.
2007 Aug
Bacterial decolorization of acid orange 7 in the presence of ionic and non-ionic surfactants.
2007 Jan-Feb
A novel technique for measuring variations in DNA copy-number: competitive genomic polymerase chain reaction.
2007 Jul 2
[Expression, purification and antigenic characterization of the Epitope-G1 gene of bovine ephemeral fever virus in Escherichia coli].
2007 Jun
Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily.
2007 Jun
Global gene expression profiling of ischemic preconditioning in the rat retina.
2007 Jun 28
Diversity of swine Bordetella bronchiseptica isolates evaluated by RAPD analysis and PFGE.
2007 Mar
Synergistic effects of chemical enhancers on skin permeability: a case study of sodium lauroylsarcosinate and sorbitan monolaurate.
2007 May
Physical analyses of E. coli heteroduplex recombination products in vivo: on the prevalence of 5' and 3' patches.
2007 Nov 28
Extensive ssDNA end formation at DNA double-strand breaks in non-homologous end-joining deficient cells during the S phase.
2007 Oct 26
Transdermal delivery enhanced by magainin pore-forming peptide.
2007 Oct 8
Optimized expression from a synthetic gene of an untagged RNase H domain of human hepatitis B virus polymerase which is enzymatically active.
2007 Sep
The major surface-associated saccharides of Klebsiella pneumoniae contribute to host cell association.
2008
Positive regulation of DNA double strand break repair activity during differentiation of long life span cells: the example of adipogenesis.
2008
CD47 associates with alpha 5 integrin and regulates responses of human articular chondrocytes to mechanical stimulation in an in vitro model.
2008
Expression and putative roles in attachment of outer membrane proteins of Escherichia coli O157 from planktonic and sessile culture.
2008 Apr
Hydrogenated fat diet intake during pregnancy and lactation modifies the PAI-1 gene expression in white adipose tissue of offspring in adult life.
2008 Apr 4
[Renaturation, purification and antigenicity identification of recombinant protein of Cysticercus cellulosae expressed in Escherichia coli].
2008 Aug
Permeabilization of baker's yeast with N-lauroyl sarcosine.
2008 Aug
Prions in milk from ewes incubating natural scrapie.
2008 Dec
Engineering inclusion bodies for non denaturing extraction of functional proteins.
2008 Dec 1
Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin.
2008 Dec 1
Evidence-based annotation of the malaria parasite's genome using comparative expression profiling.
2008 Feb 13
Differential screening of phage-ab libraries by oligonucleotide microarray technology.
2008 Jan 30
Different subcellular localizations and functions of Arabidopsis myosin VIII.
2008 Jan 8
A potential new pathway for Staphylococcus aureus dissemination: the silent survival of S. aureus phagocytosed by human monocyte-derived macrophages.
2008 Jan 9
Identification of the genetic determinants of Salmonella enterica serotype Typhimurium that may regulate the expression of the type 1 fimbriae in response to solid agar and static broth culture conditions.
2008 Jul 25
Pepper pectin methylesterase inhibitor protein CaPMEI1 is required for antifungal activity, basal disease resistance and abiotic stress tolerance.
2008 Jun
Analysis of outer membrane vesicle associated proteins isolated from the plant pathogenic bacterium Xanthomonas campestris pv. campestris.
2008 Jun 2
Apoptosis of supraoptic AVP neurons is involved in the development of central diabetes insipidus after hypophysectomy in rats.
2008 Jun 25
A polymerase III-like reinitiation mechanism is operating in regulation of histone expression in archaea.
2008 Mar
Beyond PrP9res) type 1/type 2 dichotomy in Creutzfeldt-Jakob disease.
2008 Mar 14
Synergistic enhancement of skin permeability by N-lauroylsarcosine and ethanol.
2008 Mar 20
Extracellular transglutaminase 2 is catalytically inactive, but is transiently activated upon tissue injury.
2008 Mar 26
Electromagnetic noise inhibits radiofrequency radiation-induced DNA damage and reactive oxygen species increase in human lens epithelial cells.
2008 May 19
Sequence diversity in the A domain of Staphylococcus aureus fibronectin-binding protein A.
2008 May 8
ATR-FTIR spectroscopy detects alterations induced by organotin(IV) carboxylates in MCF-7 cells at sub-cytotoxic/-genotoxic concentrations.
2008 Nov 5
Biochemical enhancement of transdermal delivery with magainin peptide: modification of electrostatic interactions by changing pH.
2008 Oct 1
Isolation and characterization of Treponema phagedenis-like spirochetes from digital dermatitis lesions in Swedish dairy cattle.
2008 Oct 20
Epidemiological study of E. coli O157:H7 isolated in Northern Ireland using pulsed-field gel electrophoresis (PFGE).
2008 Sep
Gene expression changes linked to antimicrobial resistance, oxidative stress, iron depletion and retained motility are observed when Burkholderia cenocepacia grows in cystic fibrosis sputum.
2008 Sep 19
Analysis of area-specific expression patterns of RORbeta, ER81 and Nurr1 mRNAs in rat neocortex by double in situ hybridization and cortical box method.
2008 Sep 25
EWS/ETS regulates the expression of the Dickkopf family in Ewing family tumor cells.
2009
Technical analysis of cDNA microarrays.
2009
Genomic survey of the non-cultivatable opportunistic human pathogen, Enterocytozoon bieneusi.
2009 Jan
Optical mapping of the Mycobacterium avium subspecies paratuberculosis genome.
2009 Jan 15
Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via the systemic route.
2009 Jun 19
Evaluation of procedures for outer membrane isolation from Campylobacter jejuni.
2009 Mar
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:17:41 UTC 2023
Edited
by admin
on Fri Dec 15 15:17:41 UTC 2023
Record UNII
632GS99618
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM LAUROYL SARCOSINATE
II   INCI   VANDF  
INCI  
Official Name English
SODIUM N-LAUROYL SARCOSINATE
Common Name English
SARKOSYL
Common Name English
SODIUM LAUROYL SARCOSINATE [USP-RS]
Common Name English
MEDIALAN LL-99
Brand Name English
SODIUM LAUROYL SARCOSINATE [INCI]
Common Name English
N-METHYL-N-(1-OXODODECYL)GLYCINE SODIUM SALT (1:1)
Common Name English
MEDIALAN LL-33
Brand Name English
N-LAUROYLSARCOSINE SODIUM SALT
Common Name English
NSC-117874
Code English
SODIUM LAUROYL SARCOSINATE [II]
Common Name English
GARDOL [MI]
Common Name English
GARDOL
MI  
Common Name English
SODIUM LAUROYL SARCOSINATE [VANDF]
Common Name English
SODIUM N-LAUROYLSARCOSINATE
Systematic Name English
Code System Code Type Description
RXCUI
1364901
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
CAS
137-16-6
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
WIKIPEDIA
SODIUM LAUROYL SARCOSINATE
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
MESH
C025231
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
DAILYMED
632GS99618
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
NSC
117874
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
FDA UNII
632GS99618
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
MERCK INDEX
m5671
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY Merck Index
EPA CompTox
DTXSID0027066
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
RS_ITEM_NUM
1614374
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
ECHA (EC/EINECS)
205-281-5
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
PUBCHEM
23668817
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
EVMPD
SUB20829
Created by admin on Fri Dec 15 15:17:41 UTC 2023 , Edited by admin on Fri Dec 15 15:17:41 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE