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Search results for methyl root_codes_code in Code Literal (approximate match)
Status:
Possibly Marketed Outside US
Source:
NDA021488
(2002)
Source URL:
First approved in 2002
Source:
21 CFR 333D
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Methyl pyrrolidone (or N-methyl pyrrolidone or NMP) is a small molecule acetyl‐lysine mimetic compound with potent immunomodulatory and direct anti‐myeloma activity. NMP is nontoxic, stable and already in use as a solvent in biomedical applications. This compound is under investigation in clinical trial phase I for the treatment of multiple myeloma. The study will evaluate if the NMP can be safely administered to humans at doses, which induce measurable immunological and anti-tumor effects in patients with myeloma. In addition, NMP could be useful for bone fracture repairing. NMP has shown a protective role in osteoblast differentiation in response to hypoxia, and such protection was through inhibiting the NF-κB signaling. Experiments on rodents have revealed that the compound had a remarkable anti-osteoporotic ability preserving activity in the pulp-dentine complex and preventing jawbone loss. These effects made NMP a promising candidate for the preservation of the activity of the pulp-dentin complex and jawbone thickness in post-menopausal females.
Status:
Possibly Marketed Outside US
Source:
M017
(2000)
Source URL:
First approved in 2000
Source:
M017
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
21 CFR 352
(2004)
Source URL:
First approved in 2000
Source:
ANDA075289
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M017
(2011)
Source URL:
First approved in 1998
Source:
NDA205394
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Methyl ethyl ketone (butanone) is an industrial solvent produced on a large scale. It is used in surface coatings, adhesives, printing inks, chemical intermediates, magnetic tapes, and lube oil dewaxing agents. Methyl ethyl ketone has a fruity odor similar to acetone. It is used as a flavor/fragrance agent in pharmaceuticals and cosmetics.
Status:
Possibly Marketed Outside US
Source:
ANDA078730
(1995)
Source URL:
First approved in 1995
Source:
ANDA078730
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
ANDA202230
(1995)
Source URL:
First approved in 1995
Source:
ANDA202230
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Methyl chloride, also called chloromethane, mainly is used as a refrigerant. It’s known, that methyl chloride permeates through human epidermis when exposed at high atmospheric concentrations within relatively short timeframes. Recently published article has shown that chlorinated methyl group could be formed in humans, that might be an important target compound in future medical diagnostic programs.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(1989)
Source URL:
First approved in 1989
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
NDA020489
(1953)
Source URL:
First approved in 1953
Source:
NDA020489
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Methyl laurate (methyl dodecanoate), a flavouring agent, is found in alcoholic beverages.
Status:
Possibly Marketed Outside US
Class (Stereo):
CHEMICAL (ACHIRAL)
Methyl Undecylenate is a linear ester with a terminal double bond, that can be used as a chemical intermediate in the synthesis of aromatic chemicals, of polymers or modified silicones. Methyl undecylenate is produced by fractional distillation of the product obtained by the pyrolysis of methyl ricinoleate at a high temperature. Methyl undecylenate is used as a chemical intermediate in the synthesis of organo-modified silicones for hair care preparations and sun care products. It can also be used as a chemical intermediate for synthesizing derivatives based on ammonium or ethanolamide used in hair-care products.
Status:
Other
Class:
MIXTURE