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Search results for methyl root_names_stdName in Standardized Name (approximate match)
A DNA stain used as a tracking dye in acid buffers for electrophoresis. Methyl Green was used as a topical antiseptic, however, it was withdrawn due to unwanted effects. The traditional Methyl Green has not manufactured for decades. The dye sold as Methyl Green is more accurately described as Ethyl Green. Both, Methyl Green and Ethyl Green are sold as double zinc salts.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
S-fluoxetine is an enantiomer of fluoxetine, a potent and selective inhibitor of the neuronal serotonin-uptake carrier and a clinically effective antidepressant. R-fluoxetine and S-fluoxetine enantiomers are nearly equipotent at blocking serotonin reuptake. In all biochemical and pharmacological studies, the eudismic ratio for the fluoxetine enantiomers is also near unity. A study examining the relative contributions of CYP enzymes to the metabolism of S-fluoxetine, and R-fluoxetine found dramatic differences. These data led to discovery programs between Lilly and Sepracor for the individual enantiomers. S-fluoxetine was studied in a phase 2 clinical trial for the prophylaxis of migraine, however, development was discontinued.