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Search results for m root_codes_WIKIPEDIA in WIKIPEDIA (approximate match)
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Arginyl-Glycyl-Aspartic Acid is a tripeptide composed of L-arginine, glycine, and L-aspartic acid, used as a biochemical tool in the study of cellular recognition. Arginylglycylaspartic acid hows great affinity for the integrin receptors and Arg-Gly-Asp tripeptide motif can be used for Peptide-Based Target Drug Delivery of anticancer agents. The tripeptide Arg-Gly-Asp (RGD) is an important protein sequence in the binding of proteins to cell surfaces. The RGD motif was identified in fibronectin, vitronectin, osteopontin, collagens, thrombospondin, fibrinogen, and von Willebrand factor. Many adhesive extracellular matrix, blood, and cell surface proteins recognize the RGD sequence for cell attachment.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Tenuazonic acid is one of the major Alternaria mycotoxins commonly found as a natural contaminant in food. Tenuazonic acid contamination has been linked to esophageal cancer in human populations at risk of high exposure. Tenuazonic acid inhibits protein synthesis by suppression at the ribosome. Tenuazonic acid was shown to inhibit 12-O-tetradecanoyl phorbol-13-acetate (TPA) induced ornithine decarboxylase (ODC) activity in a mouse model, and in turn suppressed mouse skin tumor promotion. In addition, this compound has been shown to be a new type of Photosystem II inhibitor.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Isopimaric acid is a widely available tricyclic diterpenoid well represented in the resin of conifers of the genera Pinus, Larix, and Picea. It exhibits interesting biological and pharmaceutical properties such as antimicrobial, antiviral, antiallergenic, and anti‐inflammatory activities. It acts as a large conductance Ca2+activated K+ channel (BK channel) opener. BK channel openers have emerged as potentially useful agents in the therapy of various diseases associated with both the central nervous system and smooth muscle system.