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Search results for "Pharmacologic Substance[C1909]|Agent Affecting Blood or Body Fluid" in comments (approximate match)
Status:
Other
Class:
POLYMER
Status:
US Previously Marketed
Source:
INNOHEP by LEO PHARMA AS
(2000)
Source URL:
First approved in 2000
Source:
INNOHEP by LEO PHARMA AS
Source URL:
Class:
POLYMER
Status:
Possibly Marketed Outside US
Source:
M020
(2022)
Source URL:
First approved in 2022
Source:
M020
Source URL:
Class:
POLYMER
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(2020)
Source URL:
First approved in 2020
Source:
21 CFR 333A
Source URL:
Class:
POLYMER
Status:
Possibly Marketed Outside US
Source:
NCT04432675: Phase 4 Interventional Completed Cesarean Section
(2022)
Source URL:
First approved in 1991
Source:
BN890105
Source URL:
Class:
POLYMER
Status:
Possibly Marketed Outside US
Class:
POLYMER
Status:
Possibly Marketed Outside US
Source:
BLA125720
(2023)
Source URL:
First approved in 2023
Source:
BLA125720
Source URL:
Class:
STRUCTURALLY DIVERSE
Status:
US Approved Rx
(2018)
Source:
NDA210238
(2018)
Source URL:
First approved in 2018
Source:
NDA210238
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Avatrombopag is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist that stimulates proliferation and differentiation of megakaryocytes from bone marrow progenitor cells resulting in increased production of platelets. Avatrombopag does not compete with TPO for binding to the TPO receptor and has an additive effect with TPO on platelet production. Avatrombopag was discovered by Yamanouchi Pharmaceutical, developed by AkaRx which late became acquired by Dova Pharmaceuticals. In 2018 avatrombopag was approved by the FDA for thrombocytopenia in adults with chronic liver disease scheduled to undergo a procedure.
Status:
US Approved Rx
(2015)
Source:
NDA206316
(2015)
Source URL:
First approved in 2015
Source:
NDA206316
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Edoxaban (DU-176b, trade names Savaysa, Lixiana) is a selective factor Xa inhibitor reduces thrombin generation and thrombus formation and is an orally bioavailable anticoagulant drug. It was developed by Daiichi Sankyo to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis and pulmonary embolism following 5-10 days of initial therapy with a parenteral anticoagulant.
Status:
US Approved Rx
(2015)
Source:
NDA204958
(2015)
Source URL:
First approved in 2015
Source:
NDA204958
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Cangrelor is a P2Y12 inhibitor that has been approved as an antiplatelet drug. It is marketed in the US under the brand name Kengreal and in Europe as Kengrexal. Cangrelor is an intravenous, direct-acting reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention.
