U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 291 - 300 of 394 results

Status:
US Approved OTC
Source:
21 CFR 349.12(d)(4) ophthalmic:demulcents polysorbate 80
Source URL:
First approved in 1949
Source:
Olothorb by Merck Sharp & Dohme
Source URL:

Class:
POLYMER


Polysorbate 80 is a nonionic surfactant and emulsifier often used in foods and cosmetics. Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the manufacture of the popular antiarrhythmic amiodarone. Polysorbate 80 is also used as an excipient in some European and Canadian influenza vaccines. Influenza vaccines contain 25 μg of polysorbate 80 per dose. Polysorbate 80 is also used in the culture of Mycobacterium tuberculosis in Middlebrook 7H9 broth. It is also used as an emulsifier in the estrogen-regulating drug Estrasorb. In Europe and America, people eat about 100 mg of polysorbate 80 in foods per day on average. Polysorbate 80 has not been found to be carcinogenic. Rats fed with diets containing up to 5% polysorbate 80 by volume for 12 weeks showed no toxic effects.
Status:
Investigational
Source:
INN:flurimedrimer (<sup>18</sup>F) [INN]
Source URL:

Class:
POLYMER

Status:
Investigational
Source:
INN:migaldendranib [INN]
Source URL:

Class:
POLYMER

Status:
Investigational
Source:
INN:acetylcysteine zidrimer [INN]
Source URL:

Class:
POLYMER

Status:
Other

Class:
POLYMER

Showing 291 - 300 of 394 results