Flurimedrimer F-18

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NCATS

Approval Year

Substance Class	Polymer Created by `admin` on `Wed Apr 02 14:23:20 GMT 2025` Edited by `admin` on `Wed Apr 02 14:23:20 GMT 2025`
Record UNII	SLJ85E4BLN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-({1-[3-(<sup>18</sup>F)fluoropropyl]-1H-1,2,3-triazol-4-yl}methoxy)ethyl ether with about 16% of hydroxyl end groups of ?,?',?'',?'''-(ethane-1,2-diyldinitrilo)tetrakis(?-hexadecakis{3-[(2-hydroxyethyl)amino]-3-oxopropyl}-dendro<sup>G4</sup>-[(3-oxopro

Preferred Name

English

Flurimedrimer F-18

Official Name

English

flurimedrimer (<sup>18</sup>F) [INN]

Common Name

English

2-Propenoic acid, methyl ester, polymer with 1,2-ethanediamine, reaction products with 1-azido-3-(fluoro-<sup>18</sup>F)propane, ethanolamine and 2-[2-(2-propyn-1-yloxy)ethoxy]ethanamine

Systematic Name

English

FLURIMEDRIMER F18 [USAN]

Common Name

English

OP-801 F-18

Code

English

Code System Code Type Description

NCI_THESAURUS

C199053

Created by admin on Wed Apr 02 14:23:20 GMT 2025 , Edited by admin on Wed Apr 02 14:23:20 GMT 2025

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INN

12599

Created by admin on Wed Apr 02 14:23:20 GMT 2025 , Edited by admin on Wed Apr 02 14:23:20 GMT 2025

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CAS

2757474-51-2

Created by admin on Wed Apr 02 14:23:20 GMT 2025 , Edited by admin on Wed Apr 02 14:23:20 GMT 2025

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FDA UNII

SLJ85E4BLN

Created by admin on Wed Apr 02 14:23:20 GMT 2025 , Edited by admin on Wed Apr 02 14:23:20 GMT 2025

PRIMARY

SMS_ID

300000051842

Created by admin on Wed Apr 02 14:23:20 GMT 2025 , Edited by admin on Wed Apr 02 14:23:20 GMT 2025

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USAN

MN-50

Created by admin on Wed Apr 02 14:23:20 GMT 2025 , Edited by admin on Wed Apr 02 14:23:20 GMT 2025

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Display Structure of Flurimedrimer F-18

Related Record Type Details


					SLJ85E4BLN

Flurimedrimer F-18

ACTIVE MOIETY

Comments:

Imaging of neuroinflammation in adults with ALS. After intravenous administration, 18F-OP-801 distributes rapidly throughout the body including across the blood brain barrier and is selectively taken up only by actively endocytosing cells (macrophage and microglia in the brain), that are associated with neuroinflammation in patients with neurodegenerative disorders such ALS

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL