Flurimedrimer F-18

Approval Year

Substance Class	Polymer Created by `admin` on `Sat Dec 16 19:13:54 UTC 2023` Edited by `admin` on `Sat Dec 16 19:13:54 UTC 2023`
Record UNII	SLJ85E4BLN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Flurimedrimer F-18

Official Name

English

2-({1-[3-(18F)fluoropropyl]-1H-1,2,3-triazol-4-yl}methoxy)ethyl ether with about 16 % of hydroxyl end groups of a regular 4-dendron poly(amidoamine)-type dendrimer

Common Name

English

flurimedrimer (<sup>18</sup>F) [INN]

Common Name

English

2-Propenoic acid, methyl ester, polymer with 1,2-ethanediamine, reaction products with 1-azido-3-(fluoro-18F)propane, ethanolamine and 2-[2-(2-propyn-1-yloxy)ethoxy]ethanamine

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C199053

Created by admin on Sat Dec 16 19:13:54 UTC 2023 , Edited by admin on Sat Dec 16 19:13:54 UTC 2023

PRIMARY

INN

12599

Created by admin on Sat Dec 16 19:13:54 UTC 2023 , Edited by admin on Sat Dec 16 19:13:54 UTC 2023

PRIMARY

CAS

2757474-51-2

Created by admin on Sat Dec 16 19:13:54 UTC 2023 , Edited by admin on Sat Dec 16 19:13:54 UTC 2023

PRIMARY

FDA UNII

SLJ85E4BLN

Created by admin on Sat Dec 16 19:13:54 UTC 2023 , Edited by admin on Sat Dec 16 19:13:54 UTC 2023

PRIMARY

Related Record Type Details


					SLJ85E4BLN

Flurimedrimer F-18

ACTIVE MOIETY

Comments:

Imaging of neuroinflammation in adults with ALS. After intravenous administration, 18F-OP-801 distributes rapidly throughout the body including across the blood brain barrier and is selectively taken up only by actively endocytosing cells (macrophage and microglia in the brain), that are associated with neuroinflammation in patients with neurodegenerative disorders such ALS

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL