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Search results for "EPA PESTICIDE" in comments (approximate match)
Status:
Possibly Marketed Outside US
Source:
21 CFR 333E
(2002)
Source URL:
First approved in 1985
Source:
ANDA078854
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
First approved in 1985
Source:
Paraguard by Seachem Laboratories Inc.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Malachite green, an N-methylated diaminotriphenylmethane dye, is used primarily as a therapeutic agent in aquaculture. It controls fungal attacks, protozoan infections and some other diseases caused by helminths on a wide variety of fish and other aquatic organisms. In solution, the dye exists as a mixture of the cation (chromatic malachite green) and its carbinol base, with the ratio depending on the pH of the solution; the dye also can undergo chemical and metabolic reduction to a leuco derivative. Malachite green intercalates with DNA, with a preference for A:T-rich regions, and the leuco derivative bears a structural resemblance to carcinogenic aromatic amines that can form covalent DNA adducts. In mammalian cells, it shows marked cytotoxicity and the ability to induce cell transformation and lipid peroxidation. The toxicity of this dye increases with exposure time, temperature and concentration. It has been reported to cause carcinogenesis, mutagenesis, chromosomal fractures, teratogenecity and respiratory toxicity.
Status:
Possibly Marketed Outside US
Source:
GINGI-PAK MAX 2-PLY by Gingi-Pak a Division of the Belport
(1984)
Source URL:
First approved in 1984
Source:
GINGI-PAK MAX 2-PLY by Gingi-Pak a Division of the Belport
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Sodium dithionite (or sodium hydrosulfite), an inexpensive and safe reducing agent, which for example enables the reduction of aromatic nitro. This compound is also used to reduce Cr(VI) to Cr(III) in chromite ore processing residue (COPR) wastes containing high available Fe.
Status:
Possibly Marketed Outside US
Source:
FUNGOID TINCTURE TREATMENT KIT-
Source URL:
First approved in 1983
Source:
Dakins Full by Century Pharmaceuticals, Inc.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
HYPOCHLORITE (as sodium salt) is a main active component of DAKIN'S® antimicrobial solution, which is used to prevent and treat infections of the skin and tissue, and also pre- and post-surgery cuts, abrasions, and skin ulcers.
Status:
Possibly Marketed Outside US
First approved in 1982
Source:
NADA113645
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
p-Chlorocresol (p-chloro-m-cresol; PCMC; brand name: Preventol CMK) possesses disinfectant and antiseptic properties. Chlorocresol is used in various preparations for skin disinfection and wounds. It also used as a preservative in creams and other preparations for external use which contain water. For use as a disinfectant such as a hand wash, it is commonly dissolved in alcohol in combination with other phenols. It is a moderate allergen for sensitive skin. Chlorocresol produces potentially life-threatening effects which include dermatitis, which are responsible for the discontinuation of chlorocresol therapy. The symptomatic adverse reactions produced by chlorocresol are more or less tolerable and if they become severe, they can be treated symptomatically, these include hypersensitivity reactions, irritation of eyes.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333E
(2013)
Source URL:
First approved in 1980
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
The iodate ion is an oxoanion of iodine bearing a negative charge and containing three oxygen atoms. Because it is more stable than iodide, most health authorities preferentially recommend iodate as an additive to salt for correcting iodine deficiency. In humans and rats, oral bioavailability of iodine from iodate is virtually equivalent to that from iodide. When given intravenously to rats, or when added to whole blood or tissue homogenates in vitro or to foodstuff, iodate is quantitatively reduced to iodide by nonenzymatic reactions, and thus becomes available to the body as iodide. Therefore, except perhaps for the gastrointestinal mucosa, exposure of tissues to iodate might be minimal. At much higher doses given intravenously (i.e., above 10 mg/kg), iodate is highly toxic to the retina. Ocular toxicity in humans has occurred only after exposure to doses of 600 to 1,200 mg per individual. Oral exposures of several animal species to high doses, exceeding the human intake from fortified salt by orders of magnitude, pointed to corrosive effects in the gastrointestinal tract, hemolysis, nephrotoxicity, and hepatic injury.
Status:
Possibly Marketed Outside US
First approved in 1978
Source:
Dairyland Brand Teat Dip by Stearns Packaging Corporation
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
DIDECYLDIMONIUM (as a salt, didecyldimethylammonium chloride (DDAC)) is used in many types of biocidal products including tableware, carpets, humidifiers, and swimming pools. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria and is also effective on fungi and viruses, including those that are enveloped.
Status:
Possibly Marketed Outside US
Source:
Cetacaine Anesthetic by Cetylite Industries, Inc.
(1960)
Source URL:
First approved in 1958
Source:
Cetacaine Anesthetic by Cetylite Industries, Inc.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Mecetronium etilsulfate (MES) is a detergent and belongs to the group of surface-active ingredients. MES along with propan-2-ol and propan-1-ol is an ingredient of rub-in hand disinfectants. The antimicrobial contribution of MES in hand rubs is questionable. MES locks on the outermost layer of the skin (stratum corneum) for sustained bacterial reduction as long as 3 to 5 hours.
Status:
Possibly Marketed Outside US
Source:
Stannous Pyrophosphate by Clarke, T.
Source URL:
First approved in 1955
Source:
Clorpactin WCS-90 by United-Guardian, Inc.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Inorganic pyrophosphate (PPi ) has long been known as a by-product of many intracellular biosynthetic reactions. PPi plays the regulatory role in living systems, such as activities of enzymes, fidelity of syntheses of macromolecules, and proliferation of cells. PPi is used as a biochemical energy source instead of ATP especially in bacteria, protists, and plants. PPi may also regulate the formation and dissolution of bone as well as pathologic calcification of soft tissues and the formation of urinary stones. The formation of calcium pyrophosphate dihydrate crystals in the extracellular fluids of joints cause the disease called pseudogout. Sodium, potassium and calcium pyrophosphates (E450) are used as food additives as buffers and emulsifiers.
Status:
Possibly Marketed Outside US
First approved in 1954
Source:
ANDA040301
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Barium hydroxide, Ba(OH)2, is also known as baryta. Barium hydroxide crystallizes as the octahydrate, which can be converted to the monohydrate by heating in air. The anhydrous hydroxide has only a secondary industrial importance; the monohydrate and octahydrate are used in industry on a far larger scale. Barium hydroxide, especially the monohydrate, is used to produce organic barium compounds such as additives for oil and stabilizers for plastics. In addition, barium hydroxide is used for dehydration and deacidification, especially for removing sulfuric acid from fats, oils, waxes, and glycerol.