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Restrict the search for
benzyl alcohol
to a specific field?
Class (Stereo):
CHEMICAL (ACHIRAL)
LAMTIDINE is an irreversible and specific gastric histamine H2-receptor antagonist.
Class (Stereo):
CHEMICAL (RACEMIC)
Becliconazole (or 1-CBCMI) is an antimycotic agent. Information about the nowadays application of this drug is not available
Class (Stereo):
CHEMICAL (RACEMIC)
Metiprenaline was developed as a bronchodilator. Information about the current use of this compound is not available.
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Tiplasinin (PAI-039) is an orally efficacious and selective plasminogen activator inhibitor-1 (PAI-1) inhibitor. Tiplasinin bound specifically to the active conformation of PAI-1 and exhibited reversible inactivation of PAI-1 in vitro. Tiplaxtinin exhibited in vivo oral efficacy in two different models of acute arterial thrombosis. The remarkable preclinical safety and metabolic stability profiles of tiplaxtinin led to advancing the compound to Phase-I clinical trial for Thrombosis, which was later discontinued.
Class (Stereo):
CHEMICAL (RACEMIC)
Cliropamine (D 16427) is a positive inotropic compound.
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Sufugolix (TAK-013 or 5-(N-benzyl-N-methylaminomethyl)-1-(2,6-difluorobenzyl)-6-[4-(3-methoxyureido)phenyl]-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione) is a highly potent and orally active non-peptide antagonist of luteinizing hormone-releasing hormone (LHRH) receptor. Sufugolix by oral administration suppresses a pituitary-ovarian axis continuously and reversibly in cynomolgus monkeys. Takeda studied Sufugolix in the trials for the treatment of endometriosis and uterine leiomyoma however development was discontinued.
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Trizoxime is an antidepressant.
Status:
Investigational
Source:
JAN:L-ISOPRENALINE HYDROCHLORIDE [JAN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Levisoprenaline (l-isoproterenol) is beta1- and beta2-adrenoreceptor agonist. In Japan, continuous inhalation of levisoprenaline is a recommended treatment for pediatric patients with acute severe exacerbation. Compared with salbutamol, l-isoproterenol reduced modified pulmonary index score more rapidly. But in most countries do not recommend continuous inhalation of l-isoproterenol to treat pediatric patients with acute severe exacerbation of asthma due to worsening asthma control. Levisoprenaline was used to cause experimental chronic heart failure in rats.
Status:
Investigational
Source:
NCT00004428: Phase 1 Interventional Completed Cystic Fibrosis
(1997)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) is a selective high-affinity antagonist radioligand for A1 adenosine receptors. DPCPX is a useful tool with which to explore the potential of activation of adenosine A1 receptors as an important mechanism in physiological and pathophysiological processes.
Status:
Investigational
Source:
NCT00106808: Phase 3 Interventional Completed Type 2 Diabetes Mellitus
(2005)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Muraglitazar previously known as BMS-298585 has been identified as a non-thiazolidinedione dual agonist of peroxisome proliferator-activated receptor alpha/gamma. Muraglitazar is currently in clinical trial phase III development for the treatment of type 2 diabetes and dyslipidemia.
