U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 2171 - 2180 of 2551 results

Status:
Investigational
Source:
INN:deterenol
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


Deterenol is a beta-adrenoceptor agonist. It is an effective nonmydriatic and nonmiotic hypotensive agent, which can be used in antiglaucoma treatment.
Status:
Investigational
Source:
INN:deterenol
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


Deterenol is a beta-adrenoceptor agonist. It is an effective nonmydriatic and nonmiotic hypotensive agent, which can be used in antiglaucoma treatment.
Status:
Investigational
Source:
INN:ketocainol
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

KETOCAINOL is an antiarrhythmic agent, anaesthetic.
Status:
Investigational
Source:
INN:propanocaine
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Propanocaine is a benzyl alcohol derivative with local anesthetics activity
Status:
Investigational
Source:
INN:elucaine
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Elucaine is local anesthetic and anti-ulcerative agent, acting as a gastric muscarinic acetylcholine receptor antagonist.
Status:
Investigational
Source:
INN:fasidotril
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Fasidotril is a diester prodrug of the active metabolite fasidotrilat. Fasidotrilat inhibited both angiotensin I converting enzyme (ACE, EC 3.4.25.1) and neprilysin (NEP, EC 3.4.24.11, also named neutral endopeptidase, enkephalinase, or atriopeptidase) at nanomolar concentrations (Ki = 9.8 nM against ACE and 5.1 nM against NEP) Fasidotril was being developed for the treatment of myocardial infarction, congestive heart failure and myocardial infarction.
Status:
Investigational
Source:
INN:asalhydromorphone [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:myrophine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Myrophine is an opiate analog and long-acting prodrug for morphine with a slow onset of effects. It is weaker than morphine as an analgesic but longer-lasting in effects and was thought to have a more local anesthetic effect than morphine, though with a somewhat greater tendency to cause histamine reactions like itching and rash. In addiction studies conducted in human subjects in the 1950s, myrophine did not substitute for morphine in withdrawal, did not produce notable morphine-like effects, and did not produce addiction or dependence regardless of dose or how it was administered.
Status:
Investigational
Source:
NCT02182804: Not Applicable Interventional Completed Esophageal Neoplasms
(2013)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Propoxycarbazone-Sodium (also known as BAY MKH 6561) is asulfonylaminocarbonyltriazolinone derivative patented by German multinational pharmaceutical and life sciences company Bayer A.-G. as herbicide Propoxycarbazone inhibits acetolactate synthase (ALS), and has selectivity on spring, winter, and durum varieties. The spectrum of control includes several species of monocot and dicot weeds at the application rates of 30 to 45 g/ha. Bromus control is the primary target since existing herbicides have limited timing, selectivity, and use patterns which reduce usefulness. Propoxycarbazone applied postemergence between the 1- to 2-leaf stage and shoot elongation has provided economic control of the following Bromus species: B. tectorum, B. secalinus, B. mollis, B. rigidus, and B. japonicus. Side effects, and sometimes control, was also noted on Aegilops tauschii for which there is no selective control outside genetically altered wheat cultivars. Broadleaf control was obtained primarily on the mustard family, including species in the genera Sisymbrium, Brassica, Descurainia, Chorispora, Camelina, Capsella, and Thlaspi. Propoxycarbazone provides control for adequate weed spectrum, however, considerations of resistance management, difficult and diverse weed pressure, and extended growing seasons will sometimes necessitate the use of sequential herbicides or mix partners.
Status:
Investigational
Source:
USAN:Amicibone
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Amicibone is an antitussive agent.

Showing 2171 - 2180 of 2551 results