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Details

Stereochemistry ABSOLUTE
Molecular Formula C38H51NO4.ClH
Molecular Weight 622.277
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MYROPHINE HYDROCHLORIDE ANHYDROUS

SMILES

Cl.[H][C@@]12OC3=C(OCC4=CC=CC=C4)C=CC5=C3[C@@]16CCN(C)[C@]([H])(C5)[C@]6([H])C=C[C@@H]2OC(=O)CCCCCCCCCCCCC

InChI

InChIKey=OIJOFEMANOKQAR-VRVMWUCTSA-N
InChI=1S/C38H51NO4.ClH/c1-3-4-5-6-7-8-9-10-11-12-16-19-34(40)42-33-23-21-30-31-26-29-20-22-32(41-27-28-17-14-13-15-18-28)36-35(29)38(30,37(33)43-36)24-25-39(31)2;/h13-15,17-18,20-23,30-31,33,37H,3-12,16,19,24-27H2,1-2H3;1H/t30-,31+,33-,37-,38-;/m0./s1

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C38H51NO4
Molecular Weight 585.8158
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED

Myrophine is an opiate analog and long-acting prodrug for morphine with a slow onset of effects. It is weaker than morphine as an analgesic but longer-lasting in effects and was thought to have a more local anesthetic effect than morphine, though with a somewhat greater tendency to cause histamine reactions like itching and rash. In addiction studies conducted in human subjects in the 1950s, myrophine did not substitute for morphine in withdrawal, did not produce notable morphine-like effects, and did not produce addiction or dependence regardless of dose or how it was administered.

Approval Year

PubMed

PubMed

TitleDatePubMed
A new genus and species of worm eels, Sympenchelys taiwanensis (Anguilliformes: Ophichthidae: Myrophinae), from the northwestern Pacific Ocean.
2015 Dec 24
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:14:54 GMT 2023
Edited
by admin
on Sat Dec 16 10:14:54 GMT 2023
Record UNII
8B8YU8Z3NG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MYROPHINE HYDROCHLORIDE ANHYDROUS
Common Name English
MORPHINE, O3-BENZYL ETHER, 6-MYRISTATE, HYDROCHLORIDE
Systematic Name English
MYROPHINE HYDROCHLORIDE
Common Name English
((4R,4AR,7S,7AR,12BS)-3-METHYL-9-PHENYLMETHOXY-2,4,4A,7,7A,13-HEXAHYDRO-1H-4,12-METHANOBENZOFURO(3,2-E)ISOQUINOLIN-7-YL) TETRADECANOATE;HYDROCHLORIDE
Systematic Name English
Code System Code Type Description
FDA UNII
8B8YU8Z3NG
Created by admin on Sat Dec 16 10:14:54 GMT 2023 , Edited by admin on Sat Dec 16 10:14:54 GMT 2023
PRIMARY
CAS
108016-75-7
Created by admin on Sat Dec 16 10:14:54 GMT 2023 , Edited by admin on Sat Dec 16 10:14:54 GMT 2023
PRIMARY
PUBCHEM
46878554
Created by admin on Sat Dec 16 10:14:54 GMT 2023 , Edited by admin on Sat Dec 16 10:14:54 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)
Related Record Type Details
ACTIVE MOIETY