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Restrict the search for
methylprednisolone acetate
to a specific field?
Class (Stereo):
CHEMICAL (ACHIRAL)
Quindecamine (also known as UCL-1407) is quinaldine derivative with antibiotic and fungicidal activity. Treatment of rats and mice with Quindecamine (250 mg/kg/ day) each day for 4 weeks followed by 500 mg/kg/day for 2 more weeks reduced spontaneous motility and body weight but produced no pathological abnormalities of the various organs studied. In vitro, the drug showed very good activity against Staphylococcus aureus, Streptococcus hemolyticus, Candida albicans, Trichophyton mentagrophytes, and T. vaginalis. The drug had very good activity in 180 human subjects with various bacterial and mycotic diseases of the skin and mucosa when applied as a 1% salve.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Class (Stereo):
CHEMICAL (ABSOLUTE)
Timobesone is a topical corticosteroid and thiol ester derivative with anti-inflammatory activity.
Class (Stereo):
CHEMICAL (MIXED)
Nexeridine, a pethidine derivative, is an opioid analgesic.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Spiroxasone is a synthetic, steroidal antimineralocorticoid of the spirolactone group patented by Merck & Co., Inc. as a diuretic and antihypertensive agent. Spiroxasone acts as potent aldosterone antagonists in animals and humans.
Status:
Investigational
Source:
JAN:JOSAMYCIN PROPIONATE [JAN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Josamycin propionate, a tasteless josamycin derivative suitable for the preparation of pediatric oral suspension. After oral administration Josamycin propionate underwent metabolic transformation to Josamycin, semi-synthetic 16-membered ring macrolide, that acts via protein synthesis inhibition.
Class (Stereo):
CHEMICAL (MIXED)
Status:
Investigational
Source:
NCT01041677: Phase 2 Interventional Completed Obesity
(2008)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Johnson and Johnson was developing usistapide, a microsomal triglyceride transfer protein (MTTP) inhibitor, for the treatment of obesity and type 2 diabetes. Usistapide, also known as JNJ-16269110 and R256918, has been used in trials studying the treatment of obesity, overweight, metabolic diseases, nutrition disorders, and nutritional and metabolic diseases. Usistapide was removed from the company pipeline and appears to have been discontinued.
Status:
Investigational
Source:
NCT03513159: Not Applicable Interventional Completed Geriatric Patients in the Transition From Hospital to Home
(2018)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Triclopyr-butotyl is an ester form of selective systemic herbicide triclopyr. Prolonged or frequently repeated skin contact with triclopyr-butotyl may cause allergic skin reactions in some individuals. Animal and in-vitro genetic studies were negative for triclopyr-butotyl. Triclopyr-butotyl did not cause cancer in laboratory animals.
Status:
Investigational
Source:
USAN:CUPRIC ACETATE CU 64 [USAN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Cu-64 is a radioisotope of copper with T1/2 12.7 hours. It decays by emission of beta+ particles with energies 0.653 (17.8%) MeV, which makes it suitable for positron emission tomography. The most widely used Cu chelators are DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) and TETA (1,4,8,11-tetraazacyclotetradecane-1,4,8,11-tetraacetic acid). Cu-64 acetate is used as a model compound to study metabolism and distribution of Cu-64.
