Details
Stereochemistry | ACHIRAL |
Molecular Formula | C30H38N4 |
Molecular Weight | 454.6495 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC(NCCCCCCCCCCNC2=CC(C)=NC3=CC=CC=C23)=C4C=CC=CC4=N1
InChI
InChIKey=GZIJBIYIMDKOSA-UHFFFAOYSA-N
InChI=1S/C30H38N4/c1-23-21-29(25-15-9-11-17-27(25)33-23)31-19-13-7-5-3-4-6-8-14-20-32-30-22-24(2)34-28-18-12-10-16-26(28)30/h9-12,15-18,21-22H,3-8,13-14,19-20H2,1-2H3,(H,31,33)(H,32,34)
Quindecamine (also known as UCL-1407) is quinaldine derivative with antibiotic and fungicidal activity. Treatment of rats and mice with Quindecamine (250 mg/kg/ day) each day for 4 weeks followed by 500 mg/kg/day for 2 more weeks reduced spontaneous motility and body weight but produced no pathological abnormalities of the various organs studied. In vitro, the drug showed very good activity against Staphylococcus aureus, Streptococcus hemolyticus, Candida albicans, Trichophyton mentagrophytes, and T. vaginalis. The drug had very good activity in 180 human subjects with various bacterial and mycotic diseases of the skin and mucosa when applied as a 1% salve.
Originator
Approval Year
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C258
Created by
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SUB10206MIG
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100000080293
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1958
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242-789-6
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C152118
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21943
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DTXSID40172538
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19056-26-9
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N28Y645EBZ
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CHEMBL125375
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)