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Details

Stereochemistry ACHIRAL
Molecular Formula C30H38N4
Molecular Weight 454.6495
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of QUINDECAMINE

SMILES

CC1=CC(NCCCCCCCCCCNC2=CC(C)=NC3=CC=CC=C23)=C4C=CC=CC4=N1

InChI

InChIKey=GZIJBIYIMDKOSA-UHFFFAOYSA-N
InChI=1S/C30H38N4/c1-23-21-29(25-15-9-11-17-27(25)33-23)31-19-13-7-5-3-4-6-8-14-20-32-30-22-24(2)34-28-18-12-10-16-26(28)30/h9-12,15-18,21-22H,3-8,13-14,19-20H2,1-2H3,(H,31,33)(H,32,34)

HIDE SMILES / InChI
Quindecamine (also known as UCL-1407) is quinaldine derivative with antibiotic and fungicidal activity. Treatment of rats and mice with Quindecamine (250 mg/kg/ day) each day for 4 weeks followed by 500 mg/kg/day for 2 more weeks reduced spontaneous motility and body weight but produced no pathological abnormalities of the various organs studied. In vitro, the drug showed very good activity against Staphylococcus aureus, Streptococcus hemolyticus, Candida albicans, Trichophyton mentagrophytes, and T. vaginalis. The drug had very good activity in 180 human subjects with various bacterial and mycotic diseases of the skin and mucosa when applied as a 1% salve.

Originator

Sources: JP40028465

Approval Year

PubMed

PubMed

TitleDatePubMed
Patents

Patents

Name Type Language
QUINDECAMINE
INN  
INN  
Official Name English
quindecamine [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C258
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
Code System Code Type Description
EVMPD
SUB10206MIG
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
PRIMARY
SMS_ID
100000080293
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
PRIMARY
INN
1958
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
PRIMARY
ECHA (EC/EINECS)
242-789-6
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
PRIMARY
NCI_THESAURUS
C152118
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
PRIMARY
PUBCHEM
21943
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
PRIMARY
EPA CompTox
DTXSID40172538
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
PRIMARY
CAS
19056-26-9
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
PRIMARY
FDA UNII
N28Y645EBZ
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
PRIMARY
ChEMBL
CHEMBL125375
Created by admin on Fri Dec 15 18:52:01 GMT 2023 , Edited by admin on Fri Dec 15 18:52:01 GMT 2023
PRIMARY