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Showing 11 - 13 of 13 results

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CYTOCHROME P450 3A5

805SU96HKF

Subunit 1 (502) Similarity Search

Sequence Search

Subunit 1 (502) Similarity Search

Status:

Other

Class:

PROTEIN

CYTOCHROME P450 3A4

PUO0521HZV

Subunit 1 (502) Similarity Search

Sequence Search

Subunit 1 (502) Similarity Search

Status:

Other

Class:

PROTEIN

NALOXEGOL OXALATE

65I14TNM33

Search for Structure

Status:

US Approved Rx (2014)

Source:

NDA204760

(2014)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=204760

First approved in 2014

Source:

NDA204760

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=204760

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Mu-type opioid receptor

Conditions:

Opioid-induced constipation

MOVANTIK (naloxegol) is a peripherally-acting mu-opioid receptor antagonist indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic noncancer pain. It is being investigated for the treatment of constipation as a side effect of prescription opioid pain medicines.

Protein

CYTOCHROME P450 3A5

Protein

CYTOCHROME P450 3A4

Structure of NALOXEGOL OXALATE

ABSOLUTE

NALOXEGOL OXALATE

Showing 11 - 13 of 13 results

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