U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 11 - 15 of 15 results

mixture
Status:
Investigational
Source:
INN:methocidin
Source URL:

Class:
MIXTURE

mixture
Status:
US Previously Marketed
Source:
SOROPON TYROTHRICIN by PURDUE
(1961)
Source URL:
First approved in 1942
Source:
Tyrothricin by Merck
Source URL:

Class:
MIXTURE



Tyrothricin is a mixture of non-ribosomal peptides produced by Brevibacillus brevis, now known as Aneurinibacillus migulanus, a gram positive aerobic bacteria. The compound mixture shows activity against bacteria, fungi and some viruses. A very interesting feature of AMPs is the fact, that even in vitro it is almost impossible to induce resistances. It is a locally effective antibiotic effective against gram-positive bacteria. It is sometimes combined with benzocaine 5 mg (Tyrozets) to provide relief from sore throats. Recommended for short-term relief of symptoms of oral and throat inflammation. Prevention of infections before/during mouth and throat operations (tooth extractions, gum surgical treatment). Tyrothricin inhibits protein biosynthesis of gram-positive organisms, but is completely ineffective against gram-negative.

Showing 11 - 15 of 15 results