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Search results for "PART 186 -- INDIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE" in comments (approximate match)
Status:
US Previously Marketed
Source:
Oleic Acid U.S.P.
(1921)
Source URL:
First marketed in 1921
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Oleic acid is an unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. Oleic acid occurs naturally in various animal and vegetable fats and oils. It is a component of the normal human diet as a part of animal fats and vegetable oils. Oleic acid may be responsible for the hypotensive (blood pressure reducing) effects of olive oil. Oleic acid has being shown to have a potential anticancer activity.
Status:
Possibly Marketed Outside US
Source:
NCT01950247: Phase 4 Interventional Unknown status Iron Deficiency Anemia (IDA)
(2013)
Source URL:
First approved in 1996
Source:
NDA021262
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Sodium chlorite (NaClO2), a sodium salt of chlorite ion, is used as a disinfectant in water treatment and as a component in therapeutic rinses and gels. NaClO2 is an active ingredient of veterinary solution AZTEC GOLD, which is used to reduce the spread of organisms, which may cause mastitis in cows. NaClO2 can increase production of reactive oxygen species, which cause the oxidative stress in human erythrocytes, and as a result, the res cell senescence.
Status:
Possibly Marketed Outside US
Source:
SURFAXIN by Chevreul, M.E.
Source URL:
First approved in 1990
Source:
21 CFR 358A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Palmitic acid is a saturated fatty acid, the principal constituent of refined palm oil, present in the diet and synthesized endogenously. Palmitic acid is able to activate the orphan G protein-coupled receptor GPR40. Palmitic acid was also a weak ligand of peroxisome proliferator-activated receptor gamma. Palmitic acid is a ligand of lipid chaperones - the fatty acid-binding proteins (FABPs). Dietary palm oil and palmitic acid may play a role in the development of obesity, type 2 diabetes mellitus, cardiovascular diseases and cancer.