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Restrict the search for
carvedilol
to a specific field?
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
(S)-carvedilol, an enantiomer of the drug carvedilol, which is used in the treatment of mild to moderate congestive heart failure. (S)-carvedilol is an alpha- and beta-adrenergic receptor blocker. It was shown, that only (S)-carvedilol caused beta-blockade. It was suggested, that the weak clinical net effect of beta-blockade of (R, S)-carvedilol at rest could be one reason why this drug causes fewer side effects than other beta-blockers, such as a reduction of nocturnal melatonin release.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
(R)-carvedilol, an enantiomer of the drug carvedilol, which is used in the treatment of mild to moderate congestive heart failure. (R)-carvedilol is an alpha adrenergic receptor blocker. It was shown, that (R)-carvedilol increased sympathetic tone, presumably as a physiological reaction to the decrease in blood pressure caused by alpha-blockade. The weak clinical net effect of beta-blockade of (R, S)-carvedilol at rest might be one reason why this drug causes fewer side effects than other beta-blockers, such as a reduction of nocturnal melatonin release.
