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Restrict the search for
m nalidixic acid
to a specific field?
Status:
Investigational
Source:
NCT00914186: Phase 2 Interventional Completed Atopic Dermatitis
(2009)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Fosfosal (2-phosphonoxybenzoic acid) is a O-phosphorylated derivative of salicylic acid used in analgesic and anti-inflammatory therapy. Fosfosal showed analgesic effect in the acetic acid-induced writhing and in the hot plate tests in mice, and showed antiinflammatory effect in the xylene induced mice ears swelling and in acetic acid induced increased vascular permeability tests in mice. Both the effects had no significant differences between fosfosal and aspirin, but the former had less stomach irritation.
Class (Stereo):
CHEMICAL (ACHIRAL)
ISOFEZOLAC is a non-steroid anti-inflammatory drug, prostaglandin synthetase inhibitor. It is indicated for use in various forms of rheumatoid arthritis and osteoarthritis.
Class (Stereo):
CHEMICAL (ACHIRAL)
Acetiamine (syn. thianeurone or diacetamine) is a thiamine derivative which is rarely used in pharmaceuticals. It is lipid-soluble. It has been studied for the treatment of rheumatic diseases.
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Duometacin is indomethacin derivative. It was developed as analgesic and anti-inflammatory agent.
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Brofezil (ICI 54594) is an ibuprofen derivative with anti-inflammatory and analgesic activity.
Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
Dapabutan an antiseptic bacteriostatic drug, active against Gram-positive bacteria. Dapabutan is a component of a local antiseptic drug Sterlane.
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Danosteine is an alkylthioacetic acid, developed by the French company Joullie International. The compound is claimed to have mucolytic action, demonstrated by inhibition of endobronchial retention of mucus induced by inhalation of SO2 in rats.
Class (Stereo):
CHEMICAL (RACEMIC)
Iolixanic Acid is triiodophenoxyalkoxyalkanoic acid derivative patented by Bracco Industria Chimica S.p.A. as diagnostic agent for cholecystography.
Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Glutaurine is formed from the amino group of taurine with the gamma-carboxy group of L-glutamic acid. It was originally discovered in the parathyroid. Evidence has been found suggesting that glutaurine plays a role in peripheral thyroid hormonal regulation. Glutaurine increases triiodothyronine (T3) levels, but does not alter thyroxine (T4) levels. Glutaurine was also shown to prevent electroconvulsive shock-induced amnesia by counteracting the shock effect on the memory consolidation phase. Other roles that have been suggested for glutaurine include roles as a mouse metabolite, a mammalian metabolite, a human metabolite, an anticonvulsant, an anxiolytic drug and a hormone.
