Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C17H20O5S |
| Molecular Weight | 336.403 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC2=CC=C(C=C2C=C1)[C@H](C)C(=O)OCCS(C)(=O)=O
InChI
InChIKey=JGBUBSOKFSVXKS-LBPRGKRZSA-N
InChI=1S/C17H20O5S/c1-12(17(18)22-8-9-23(3,19)20)13-4-5-15-11-16(21-2)7-6-14(15)10-13/h4-7,10-12H,8-9H2,1-3H3/t12-/m0/s1
Naproxen etemesil is a lipophilic, non-acidic, inactive prodrug of the non-steroidal anti-inflammatory drug (NSAID) naproxen that is hydrolysed to pharmacologically active naproxen once absorbed. Naproxen etemesil was in development with Logical Therapeutics for the treatment of osteoarthritis. However, no recent development has been reported. It is also in phase I clinical trials for the treatment of inflammation and arthritis.The compound was originally developed by Medinox, licensed to Logical Therapeutics in 2006 for partial rights.
Originator
Approval Year
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DB12398
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25170420
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214269U36R
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SUB127210
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100000153206
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DTXSID60191903
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385800-16-8
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CHEMBL2105683
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C166529
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WW-75
Created by
admin on Fri Dec 15 17:32:00 UTC 2023 , Edited by admin on Fri Dec 15 17:32:00 UTC 2023
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SUBSTANCE RECORD
