U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C11H21Cl2O4P
Molecular Weight 319.162
Optical Activity ( + / - )
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of VINCOFOS

SMILES

CCCCCCCCOP(=O)(OC)OC=C(Cl)Cl

InChI

InChIKey=HTBIRVYBBVMZPP-UHFFFAOYSA-N
InChI=1S/C11H21Cl2O4P/c1-3-4-5-6-7-8-9-16-18(14,15-2)17-10-11(12)13/h10H,3-9H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C11H21Cl2O4P
Molecular Weight 319.162
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Vincofos is a broad-spectrum canine anthelmintic. All or nearly all of the ascarids, hookworms, whipworms, and the tapeworm, Taenia pisiformis, were expelled following therapy with vincofos. The tapeworm, Dipylidium caninum, was also effectively removed by the vincofos treatment, but it appeared that a slightly greater dosage would be required to obtain maximum anthelmintic effect.

Approval Year

PubMed

PubMed

TitleDatePubMed
Toxicity of an organic phosphate anthelmintic (Shell SD 15803) at excessive dosages in two-month-old pony foals.
1972 Feb
Evolution of an anthelmintic: vincofos.
1974 Jan

Sample Use Guides

Dogs: The vincofos was prepared as an oil solution in soft gelatin capsules and administered orally as a single dose of 18 mg/kg.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:28:36 GMT 2023
Edited
by admin
on Fri Dec 15 17:28:36 GMT 2023
Record UNII
29477EFT4J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VINCOFOS
INN   USAN  
INN   USAN  
Official Name English
SD-15803
Code English
SD 15803
Code English
vincofos [INN]
Common Name English
2,2-Dichlorovinyl methyl octyl phosphate
Systematic Name English
VINCOFOS [USAN]
Common Name English
PHOSPHORIC ACID, 2,3-DICHLOROETHENYL METHYL OCTYL ESTER
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C250
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
Code System Code Type Description
MESH
C009666
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
PRIMARY
INN
3306
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
PRIMARY
NCI_THESAURUS
C152881
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
PRIMARY
CAS
17196-88-2
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
PRIMARY
EPA CompTox
DTXSID80864743
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
PRIMARY
FDA UNII
29477EFT4J
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
PRIMARY
PUBCHEM
66388
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
PRIMARY
ChEMBL
CHEMBL2104915
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
PRIMARY
SMS_ID
100000079088
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
PRIMARY
EVMPD
SUB00057MIG
Created by admin on Fri Dec 15 17:28:36 GMT 2023 , Edited by admin on Fri Dec 15 17:28:36 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY