U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1841 - 1850 of 2893 results

Status:
Possibly Marketed Outside US
Source:
Canada:GLYOXAL
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Glyoxal refers to the reactive electrophilic species (RES) and is formed during different processes, e.g., lipid peroxidation, DNA oxidation. RES cause the damage of proteins and nucleotides and thus can cause different diseases in human, e.g., diabetes. Glyoxal reacting with free guanines in RNAs can be is used for chemical probing of RNA structure.
Diethyltoluamide (DEET) is an insect repellent used to keep insects away. This product is effective against mosquitoes, biting flies (gnats, sandflies, deer flies, stable flies, black flies), ticks, harvest mites, and fleas. DEET is absorbed through the skin. DEET has few adverse effects when applied as directed. The most common problem is local skin irritation, including erythema and pruritis, at the site of application.
Status:
Possibly Marketed Outside US
Source:
ZO Skin Health Exfoliating Cleanser by ZO Skin Health, Inc.
(2017)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Caprylic alcohol (also known as 1-octanol) is long-chain alcohol used to prevent foaming. The Caprylic alcohol has been demonstrated to effectively alleviate tremor symptoms in ET without causing intoxication or other clinically relevant adverse effects. Pharmacokinetic findings suggested that the effect of 1-octanol might be mediated through its metabolite octanoic acid.
Bornyl acetate is the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, which has displayed an anti-inflammatory effect. In addition was shown, that this compound had therapeutic potentials for the osteoarthritis and may be developed as a preventive agent for lung inflammatory diseases. In combination with 5-fluorouracil, bornyl acetate possesses the anticancer activity by inducing apoptosis, DNA fragmentation as well as G2/M cell cycle arrest.
Status:
Possibly Marketed Outside US
Source:
StepSept pH Down by BouMatic, LLC
(2014)
Source URL:
First approved in 2014

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Urea sulfate is used as a desiccant and defoliant and functions as a cell membrane disruptor. It is used to kill bacteria on potatoes, in milking equipment, and within food processing areas. The herbicide is non-toxic to animals and birds. It is a severe skin and eye irritant.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Diethylene glycol monomethyl ether is a ether-alcohol derivative. The ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. Diethylene glycol monomethyl ether (DEGME) is sold by Dow under the tradename Methyl CARBITOL™ solvent. DEGME is an ethylene-series or E-series glycol ether. It is primarily used as a de-icing additive for aviation fuel.

Showing 1841 - 1850 of 2893 results