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Details

Stereochemistry ACHIRAL
Molecular Formula C8H18O
Molecular Weight 130.2279
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CAPRYLIC ALCOHOL

SMILES

CCCCCCCCO

InChI

InChIKey=KBPLFHHGFOOTCA-UHFFFAOYSA-N
InChI=1S/C8H18O/c1-2-3-4-5-6-7-8-9/h9H,2-8H2,1H3

HIDE SMILES / InChI
Molecular Formula C8H18O
Molecular Weight 130.2279
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Caprylic alcohol (also known as 1-octanol) is long-chain alcohol used to prevent foaming. The Caprylic alcohol has been demonstrated to effectively alleviate tremor symptoms in ET without causing intoxication or other clinically relevant adverse effects. Pharmacokinetic findings suggested that the effect of 1-octanol might be mediated through its metabolite octanoic acid.

Approval Year

2014
503
PubMed

PubMed

TitleDatePubMed
[Genetic aspects of species structure of the compost worm Eisenia foetida (Sav.) (Oligochaeta, Lumbricidae)].
2002-03-08
Syntheses, derivatives, solubility, and interfacial properties of 2-methyl-2-polyfluoroalkenyloxymethyl-1,3-propanediols: potential building blocks for syntheses of amphiphatic macromolecules.
2002-03-08
The relative partitioning of neutral and ionised compounds in sodium dodecyl sulfate micelles measured by micellar electrokinetic capillary chromatography.
2002-03
Antioxidant properties of trans-epsilon-viniferin as compared to stilbene derivatives in aqueous and nonaqueous media.
2002-02-27
Sequential injection 90Sr determination in environmental samples using a wetting-film extraction method.
2002-02-15
Enantioselective analysis of atenolol in biologic fluids: comparison of liquid-liquid and solid-phase extraction methods.
2002-02-05
Detection and quantification of ochratoxin A and deoxynivalenol in barley grains by GC-MS and electronic nose.
2002-02-05
Specific gap junctions enhance the neuronal vulnerability to brain traumatic injury.
2002-02-01
Photodegradation studies on lacidipine in solution: basic experiments with a cis-trans reversible photoequilibrium under UV-A radiation exposure.
2002-02-01
Molecular diversity sample generation on the basis of quantum-mechanical computations and principal component analysis.
2002-02
Effects of primary alcohols on airway smooth muscle.
2002-02
The effect of the nature of H-bonding groups on diffusion through PDMS membranes saturated with octanol and toluene.
2002-02
Astrocyte Ca2+ waves trigger responses in microglial cells in brain slices.
2002-02
[Synthesis of alkyl glycosides, catalyzed by beta-glycosidases in a reversed micelle system].
2002-01-29
Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties.
2002-01-25
Carboxylates stacked over aromatic rings promote salt bridge formation in water.
2002-01-23
Synthesis and characterization of a series of novel monoacylated ascorbic acid derivatives, 6-O-acyl-2-O-alpha-D-glucopyranosyl-L-ascorbic acids, as skin antioxidants.
2002-01-17
Rapid determination of partition coefficients between n-octanol/water for cardiovascular therapies.
2002-01-10
Partitioning of polychlorinated biphenyls and hexachlorobenzene into human faeces.
2002-01
Intercellular coupling among interstitial cells of Cajal in the guinea pig small intestine.
2002-01
A dynamic method of measuring surface potential change due to binding of bitter substance at monolayer-coated liquid membrane surface.
2002-01
Synthesis, structure, spectroscopic properties, and electrochemistry of rare earth sandwich compounds with mixed 2,3-naphthalocyaninato and octaethylporphyrinato ligands.
2001-12-03
Headspace solvent microextraction.
2001-12-01
Novel enzymatic assay for determination of alkyl polyglycosides with short chain fatty alcohols.
2001-12
Fast and direct method for measuring 1-octanol-water partition coefficients exemplified for six local anesthetics.
2001-12
Dense nonaqueous phase liquid tracer tests: experimental results.
2001-12
Fullerene modified supported lipid membrane as sensitive element of sensor for odorants.
2001-12
Energetics of side chain packing in staphylococcal nuclease assessed by exchange of valines, isoleucines, and leucines.
2001-11-20
Comparison of the effect of fatty alcohols on the permeation of melatonin between porcine and human skin.
2001-11-09
A gap junctionally transmitted epithelial cell signal regulates endocytic yolk uptake in Oncopeltus fasciatus.
2001-11-01
[Extraction and stripping of H acid and DSD acid wastewater].
2001-11
Partitioning of polycyclic aromatic hydrocarbons in the polyethylene/water system.
2001-11
Regiospecific effect of 1-octanol on cis-trans isomerization of unsaturated fatty acids in the solvent-tolerant strain Pseudomonas putida S12.
2001-11
Involvement of connexin 43 in meiotic maturation of bovine oocytes.
2001-10
Dual action of n-alcohols on neuronal nicotinic acetylcholine receptors.
2001-10
[Pretreatment of benzoic acid wastewater].
2001-09
pH-Metric log K calculations of famotidine, naproxen, nizatidine, ranitidine and salicylic acid.
2001-09
Pharmacokinetics of EF5 [2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide] in human patients: implications for hypoxia measurements in vivo by 2-nitroimidazoles.
2001-09
Galactosyl transfer catalyzed by thermostable beta-glycosidases from Sulfolobus solfataricus and Pyrococcus furiosus: kinetic studies of the reactions of galactosylated enzyme intermediates with a range of nucleophiles.
2001-09
Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability?
2001-09
Preparative isolation and purification of six diterpenoids from the Chinese medicinal plant Salvia miltiorrhiza by high-speed counter-current chromatography.
2001-08-03
Influence of structural variation in room-temperature ionic liquids on the selectivity and efficiency of competitive alkali metal salt extraction by a crown ether.
2001-08-01
Simultaneous prediction of aqueous solubility and octanol/water partition coefficient based on descriptors derived from molecular structure.
2001-08
Enantiomeric separation and quantitative determination of propranolol in tablets by chiral high-performance liquid chromatography.
2001-08
ATP suppresses the K(+) current responses to FSH and adenosine in the follicular cells of Xenopus oocyte.
2001-08
Non-invasive methods for absolute cerebral blood flow measurement using 99mTc-ECD: a study in healthy volunteers.
2001-07
Joint QSAR analysis using the Free-Wilson approach and quantum chemical parameters.
2001
Connexin-mimetic peptide Gap 27 decreases osteoclastic activity.
2001
Water treatment by TiO2 photocatalysis and/or ultrasound: degradations of phenyltrifluoromethylketone, a trifluoroacetic-acid-forming pollutant, and octan-1 -ol, a very hydrophobic pollutant.
2001
Prolonged epileptiform bursting induced by 0-Mg(2+) in rat hippocampal slices depends on gap junctional coupling.
2001
Patents

Patents

04073770
1
04152518
2
04481202
1
04892680
1
05104989
1
05137653
1
05151432
2
05260051
3
05260311
9
05310500
3
05328925
9
05675013
1
05712297
9
05753683
6
06130346
1
06242636
1
06509400
1
06541549
1
06787550
1
06977298
4
07271297
1
JP2004203872A
4
JP2004514645A
2
JP2004534059A
5
JP2005320508A
1
JP2005516813A
1
JP2007169576A
1
JP2008056555A
1
JP2008246002A
1
JP2009286934A
1
JP4834290B2
3
JPH01128909A
1
JPH01304052A
1
JPH0270708A
1
JPH0382812A
1
JPH05155810A
1
JPH05946A
2
JPH06107996A
2
JPH06192160A
1
JPH0799927A
1
JPH08104662A
1
JPH1147586A
1
JPH1180082A
2
JPS54160546A
5
JPS5531056A
1
JPS5634752A
1
JPS5899418A
1
JPS60234590A
1
JPS6032749A
2
JPS6087264A
2
JPS6389520A
1

Sample Use Guides

In Vivo Use Guide
1 mg/kg - 64 mg/kg
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Wed Apr 02 18:54:54 GMT 2025
Edited
by admin
on Wed Apr 02 18:54:54 GMT 2025
Record UNII
NV1779205D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CAPRYLIC ALCOHOL
Common Name English
CAPRYLYL ALCOHOL
INCI  
INCI  
Preferred Name English
1-N-OCTANOL
Common Name English
1-OCTANOL [FHFI]
Common Name English
NACOL 8-99 ALCOHOL
Brand Name English
N-OCTYL ALCOHOL
Common Name English
KALCOHL-0898
Code English
1-OCTANOL
FHFI   HSDB   MI  
Systematic Name English
1-OCTANOL [HSDB]
Common Name English
CO-898
Code English
ALFOL 8 ALCOHOL
Brand Name English
N-OCTYL ALCOHOL, PRIMARY
Common Name English
OCTYL ALCOHOL [FCC]
Common Name English
LOROL C 8-98
Code English
FEMA NO. 2800
Code English
OCTYL ALCOHOL
FCC  
Systematic Name English
1-OCTANOL [MI]
Common Name English
N-OCTANOL
Common Name English
NSC-9823
Code English
HEPTYL CARBINOL
Systematic Name English
Classification Tree Code System Code
JECFA EVALUATION 1-OCTANOL
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
CFR 21 CFR 172.515
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
EPA PESTICIDE CODE 79037
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
CFR 21 CFR 172.230
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
Code System Code Type Description
MERCK INDEX
m8110
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY Merck Index
RXCUI
1487826
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY RxNorm
CAS
111-87-5
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
CHEBI
16188
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
DRUG BANK
DB12452
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
EPA CompTox
DTXSID7021940
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
FDA UNII
NV1779205D
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
CHEBI
37868
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
PUBCHEM
957
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
SMS_ID
100000127439
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
ECHA (EC/EINECS)
203-917-6
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
NSC
9823
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
JECFA MONOGRAPH
268
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
HSDB
700
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
WIKIPEDIA
1-Octanol
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
DAILYMED
NV1779205D
Created by admin on Wed Apr 02 18:54:54 GMT 2025 , Edited by admin on Wed Apr 02 18:54:54 GMT 2025
PRIMARY
NIH
NCATS
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