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Search results for m root_names_stdName in Standardized Name (approximate match)
Class (Stereo):
CHEMICAL (ABSOLUTE)
LANPROSTON is an analog of prostaglandin F2 alpha. It is used as veterinary medicament.
Class (Stereo):
CHEMICAL (ACHIRAL)
LAMTIDINE is an irreversible and specific gastric histamine H2-receptor antagonist.
Class (Stereo):
CHEMICAL (ACHIRAL)
Colfenamate is an antypyretic and antiinflammatory compound developed by the German company Tropon, GmbH.
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Liarozole is an imidazole-containing compound that inhibits the cytochrome P-450-dependent metabolism of all-trans-retinoic acid (RA). Liarozole, a retinoic acid (RA) metabolism-blocking agent
(RAMBA) in clinical development, has been granted orphan
drug designation for congenital ichthyosis by the European
Commission and the U.S. Food and Drug Administration. Later, based on the mixed results from a phase II/III trial of liarozole for the treatment of ichthyosis, Barrier decided to discontinue the development of liarozole. Liarozole displays antitumor activity against androgen-dependent and independent rat prostate carcinomas.A large phase III international study was completed
comparing liarozole 300 mg twice daily with cyproterone
acetate (CPA) 100 mg twice daily in a total of 321
patients with metastatic prostate cancer in relapse after
first-line endocrine therapy. The results
indicate that liarozole might be a possible treatment
option for prostate cancer (PCA) following failure of
first-line endocrine therapy.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Ambamustine (PTT-119) is a bifunctional alkylating agent. Its antitumour effect is reported to mainly be through alkylation and interstrand cross-linkage of DNA. The drug was awaiting registration in Italy for the treatment of non-Hodgkin's lymphoma, and was also in phase-II clinical trial for small cell lung cancer, but was discontinued.
Status:
Investigational
Source:
INN:brosuximide [INN]
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Brosuximide is longer-lasting anticonvulsant that has been studied as an antiepileptic drug.
Status:
Investigational
Source:
INN:fepentolic acid [INN]
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
FEPENTOLIC ACID is a choleretic agent.
Class (Stereo):
CHEMICAL (MIXED)
Etanterol (VAL 481), a phenethanolamine derivative, is a β2 adrenoceptor agonist that was undergoing phase II trials in Italy as a bronchodilator with Valeas.
Status:
Class (Stereo):
CHEMICAL (ACHIRAL)
ISOMETAMIDIUM (as a chloride salt) is widely used in tropical countries as an antiprotozoal agent to control animal trypanosomiasis. It is used principally in cattle but also in sheep, goats, buffalos, donkeys, horses, camels and dogs.
Class (Stereo):
CHEMICAL (RACEMIC)
Oxoprostol was developed as a gastric acid secretion inhibitor. Information about the further development of this drug is not available.