Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C28H26N7 |
| Molecular Weight | 460.5529 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 1 |
SHOW SMILES / InChI
SMILES
CC[N+]1=C(C2=CC=CC=C2)C3=C(C=CC(N\N=N\C4=CC(=CC=C4)C(N)=N)=C3)C5=CC=C(N)C=C15
InChI
InChIKey=UGKOYGZYLRKTJH-UHFFFAOYSA-O
InChI=1S/C28H25N7/c1-2-35-26-16-20(29)11-13-24(26)23-14-12-22(17-25(23)27(35)18-7-4-3-5-8-18)33-34-32-21-10-6-9-19(15-21)28(30)31/h3-17,29H,2H2,1H3,(H4,30,31,32,33)/p+1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Cationic antitrypanosomal and other antimicrobial agents in the therapy of experimental Pneumocystis carinii pneumonia. | 1988 Jun |
|
| New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii. | 1995 Nov 24 |
|
| Therapeutic and prophylactic effects of isometamidium chloride (Samorin) against the hemoflagellate Cryptobia salmositica in chinook salmon (Oncorhynchus tshawytscha) and the effects of the drug on uninfected rainbow trout (O. mykiss). | 2001 Jan |
|
| Monitoring the correct use of isometamidium by farmers and veterinary assistants in Eastern Province of Zambia using the isometamidium-ELISA. | 2002 Dec 11 |
|
| Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda. | 2002 Oct |
|
| Field studies of drug-resistant cattle trypanosomes in Kénédougou Province, Burkina Faso. | 2003 Apr |
|
| Protective efficacy of isometamidium chloride and diminazene aceturate against natural Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population in Uganda. | 2004 Sep |
|
| Evaluation of isometamidium levels in the serum of sheep and goats after prophylactic treatment against trypanosomosis. | 2004 Sep |
|
| Rapid identification of isometamidium-resistant stocks of Trypanosoma b. brucei by PCR-RFLP. | 2006 Aug |
|
| Metabolism of isometamidium in hepatocytes isolated from control and inducer-treated rats. | 2006 Dec |
|
| Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania. | 2006 Feb |
|
| Isometamidium sensitivity of Trypanosoma congolense stocks from cattle in West Africa tested in mice and the drug incubation infectivity test. | 2006 Jan |
|
| The history of African trypanosomiasis. | 2008 Feb 12 |
|
| Development and validation of an improved HPLC method for the control of potentially counterfeit isometamidium products. | 2008 Jan 7 |
|
| Health management of horses under high challenge from trypanosomes: a case study from Serengeti, Tanzania. | 2008 Jul 4 |
|
| Does isometamidium chloride treatment protect tsetse flies from trypanosome infections during SIT campaigns? | 2008 Jun |
|
| Prevalence of bovine trypanosomosis and trypanocidal drug sensitivity studies on Trypanosoma congolense in Wolyta and Dawero zones of southern Ethiopia. | 2008 Mar 25 |
|
| Molecular tools for the rapid detection of drug resistance in animal trypanosomes. | 2008 May |
|
| Assessment of the occurrence of trypanocidal drug resistance in trypanosomes of naturally infected cattle in the Adamaoua region of Cameroon using the standard mouse test and molecular tools. | 2008 May |
|
| Advancing drug innovation for neglected diseases-criteria for lead progression. | 2009 Aug 25 |
|
| Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal. | 2009 Sep 29 |
|
| Immunology and cell biology of parasitic diseases. | 2010 |
|
| Immunobiology of African trypanosomes: need of alternative interventions. | 2010 |
|
| Immunological and therapeutic strategies against salmonid cryptobiosis. | 2010 |
|
| Dyes, trypanosomiasis and DNA: a historical and critical review. | 2010 Dec |
|
| The killing of African trypanosomes by ethidium bromide. | 2010 Dec 16 |
|
| Diverse effects on mitochondrial and nuclear functions elicited by drugs and genetic knockdowns in bloodstream stage Trypanosoma brucei. | 2010 May 4 |
|
| Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracyclines and enrofloxacin. | 2010 Sep 28 |
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| Classification Tree | Code System | Code | ||
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WHO-VATC |
QP51AX19
Created by
admin on Fri Dec 15 16:00:11 GMT 2023 , Edited by admin on Fri Dec 15 16:00:11 GMT 2023
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| Code System | Code | Type | Description | ||
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300000044835
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C83842
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20438-03-3
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DTXSID30174384
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S9HA0WUW3H
Created by
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Isometamidium
Created by
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72452
Created by
admin on Fri Dec 15 16:00:11 GMT 2023 , Edited by admin on Fri Dec 15 16:00:11 GMT 2023
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PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
