Pirandamine is the potential antidepressant drug. It is a relatively selective inhibitor of the serotonin uptake mechanism and does not exhibit appreciable norepinephrine uptake blocking activity in contrast to the tricyclic antidepressant drugs imipramine and amitriptyline. Pirandamine is equivalent to amitriptyline and greater than imipramine in potency as a serotonin uptake blocker and a potentiator of central serotonin pharmacological actions, and in contrast, does not exhibit appreciable central anticholinergic effects. Pirandamine potentiated the behavioral effects of 5-hydroxytryptophan in mice. Pirandamine, in contrast to desimipramine and imipramine, did not prevent reserpine-induced hypothermia. The (-)-enantiomer of pirandamine retained the activity of the racemate; the (+I-enantiomer was much less effective.

Ortetamine, also known as 2-methylamphetamine, is a monoamine releaser that was studied as a stimulant drug. Information about the current use of this drug is not available.

Lonaprofen is an analgesic, antipyretic and anti-inflammatory agent.

Dichlormezanone is the skeletal muscle relaxant. This metathiazanone was found to have a mephenesin-like type of action characterized by paralyzing, anticonvulsant, and hypothermic activities. Dichlormezanone produced an ascending type of paralysis, associated with a marked ataxia. It has anti-electroshock and anti-chemoshock activities. It was found to be active after oral administration and to have a prolonged duration of action. The daily administration of sublethal doses of dichlormezanone to albino rats for 5 consecutive days produced only an initial loss of weight. No significant hematologic alteration or macroscopic lesion of any of the viscera, attributable to medication with either drug, was observed.

Ethomoxane is antagonist of alpha-adrenoreceptor exerting antihypertensive properties.

Butocrolol amino alcohol derivative with β-adrenolytic, antiarrhythmic, and local anesthetic properties having sympatholytic and antiarrhythmic effects comparable to those of propranolol, but with lower local anesthetic effects.

Morpheridine is a pethidine analog with strong analgesic activity. Morpheridine does not cause convulsions, although it produces the standard opioid side effects such as sedation and respiratory depression. Morpheridine is not currently used in medicine and is a Schedule I drug which is controlled under United Nations drug conventions.

Butopiprine is alkoxyethyl α-phenyl-α-piperidinoacetate possessing spasmolytic, local anesthetic, and antitussive activity.