U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1421 - 1430 of 1728 results

Status:
Investigational
Source:
INN:laurolinium acetate
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

LAUROLINIUM, a quaternary ammonium compound, is a cationic antimicrobial agent. It has a broad spectrum of activity against Gram‐positive and Gram‐negative bacteria, fungi, and protozoan Trichomonas vaginalis. It is suitable for use in the treatment of local infections, for the sterilization of skin areas and for general antiseptic purposes.
Status:
Investigational
Source:
INN:furodazole
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Furodazole, a benzimidazole derivative was studied as an anthelmintic drug. Information about the current use of this compound is not available.
Status:
Investigational
Source:
INN:penoctonium bromide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Penoctonium, a chemotherapeutic agent was used in microbial studies. However, information about the further development of this compound is not available.
Status:
Investigational
Source:
INN:sepazonium chloride
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Sepazonium was studied as a topical anti-infective drug. However, information about the current use of this agent is not available.
Status:
Investigational
Source:
INN:difloxacin
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Difloxacin is an aryl fluoroquinolone derivative. The primary bacterial target of fluoroquinolones is the enzyme deoxyribonucleic acid gyrase. Difloxacin is very potent against a broad spectrum of bacteria including aerobic ana anaerobic gram-positive and gram-negative oragnisms. DICURAL® (difloxacin hydrochloride) TABLETS are indicated for the management of diseases in dogs associated with bacteria susceptible to difloxacin.
Status:
Investigational
Source:
NCT00612508: Not Applicable Interventional Completed Contraceptive Usage
(2007)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Dofamium is the antiseptic agent. It was used for the water sterilization.
Status:
Investigational
Source:
INN:opratonium iodide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
NCT00446134: Phase 2 Interventional Completed Chronic Hepatitis C
(2007)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Taribavirin, an oral prodrug of ribavirin that was developed as nucleoside antimetabolite, which interferes with duplication of viral genetic material. Taribavirin was studied in phase III clinical trial for the treatment of chronic hepatitis C patients. However, this drug not yet approved for pharmaceutical use.
Status:
Investigational
Source:
INN:sanfetrinem [INN]
Source URL:

Class (Stereo):
CHEMICAL (EPIMERIC)

Sanfetrinem cilexetil (formerly known as GV 118819), a beta-lactam antibiotic, is the oral prodrug of sanfetrinem. Experiments on rodents have revealed that sanfetrinem cilexetil had strong antibacterial activity in vitro and good pharmacokinetic behavior in mice. This drug was suitable for the treatment of infections caused by a variety of bacteria and participated in a phase II clinical trial. However, this study was discontinued.
Status:
Investigational
Source:
INN:zinoconazole
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Zinoconazole, an imidazole derivative that was used as an antifungal agent. Information about the current use of this compound is not available.

Showing 1421 - 1430 of 1728 results