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Search results for amphotericin root_notes_note in Note (approximate match)
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Enniatin B is a cyclic hexadepsipeptide it contains three N-methyl-Lvaline and three a-hydroxy-D-isovaleric molecules. It is generated by multiple Fusarium strains. It has ionophoric, antibiotic and insecticidal activity. A mixture of Enniatins A, A1, B and B1 (called fusafungine) was originally patented as local antibiotic for the topically treatment of nose and throat infections. Enniatin B is a mycotoxin contaminant found in vegetables, cereals and coffee. Enniatin B did not show genotoxic activity but demonstrated cytotoxicity at low micromolar concentrations. The observed activities included the specific inhibition of acyl-CoA cholesterol acyltransferase, depolarization of mitochondria, inhibition of osteoclastic bone resorption, and induction of apoptosis in cancer cells as well as the interaction with ATP-binding cassette transporters such as P-glycoprotein. Enniatin B demonstrated synergistic activity against cervical cancer in vitro and in vivo.
Zinc tetrafluoroborate is a starting material for homometallic, trinuclear heteroscorpionate complexes, which are applied in studies of electronic and magnetic properites. It is used as mild Lewis acid catalyst for various reactions.
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Syringin is a compound, extracted from Eleutherococcus senticosus. It is a component of herbs, which are used in traditional Chinese medicine. Several studies have demonstrated the multiple pharmacological properties of syringin, including anti-inflammatory, anti-tumor, and immunomodulatory effect. It was tested in several preclinical studies against type 2 diabetes, cardiac hypertrophy, edema, and arthritis. Syringin was shown to inhibit ICAM-1 expression and is considered as a possible treatment for acute gout.